Pomegranate | vital.ly

Pomegranate

Scientific names: Punica granatum

Family: Lythraceae

Alternate names: Anardana, Dadim, Dadima, Delima, Extrait de Feuille de Grenade, Extrait de Grenade, Extrait de Polyphénol de Grenade, Feuille de Grenade, Fleur de Grenade, Fruit du Grenadier, Fruit of the Dead, Gangsalan, Granaatappel, Granad, Granada, Granado, Granatapfel, Grenade, Grenadier, Limoni, Melogranato, Melograno Granato, PE, PLE, Pomegranate Extract, Pomegranate Flower, Pomegranate Fruit, Pomegranate Leaf, Pomegranate Leaf Extract, Pomegranate Polyphenol Extract, Pomme Grenade, Pomo Granato, Pomo Punico, PPE, Roma, Romazeira, Romeira, Shi Liu Gen Pi, Shi Liu Pi, Tab Tim

Actions: Analgesic, Antiallergic, Antiatherogenic, Anticoagulant, Antidiarrheal, Antifungal, Anti-inflammatory, Antimalarial, Antimicrobial, Antimutagenic, Antineoplastic, Antioxidant, Antiparasitic, Antiviral, Bone, Cardiovascular, Cholesterol-lowering, Dermatologic, Erectile function, Fertility, Gastrointestinal, Hematological, Hepatic, Hormonal, Hypoglycemic, Hypotensive, Immune, Kidney, Memory, Neurological, Uterine stimulant, Weight loss, Wound-healing

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Scientific names: Punica granatum

Family: Lythraceae

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Background

Pomegranate (Punica granatum) is a small fruit-bearing tree. The fruit is commonly eaten as a food and has also been used medicinally in various cultures.

Pomegranate contains chemicals that might have antioxidant effects. One pomegranate delivers almost 30 mg of vitamin C. Other chemicals in pomegranate juice might slow hardening of the arteries and possibly fight cancer cells.

People use pomegranate for high blood pressure, athletic performance, heart disease, diabetes, and many other conditions, but there is no good scientific evidence to support most of these uses. There is also no good evidence to support using pomegranate for COVID-19.

Safety Safety definitions

When taken by mouth: Pomegranate fruit and fruit juice are likely safe for most people. Most people don't experience side effects and it's been used safely for up to 3 years. Pomegranate fruit and seed extract are possibly safe. Some people have experienced allergic reactions, including itching, swelling, runny nose, and difficulty breathing.

The root, stem, and peel of pomegranate are possibly unsafe when used in large amounts. They contain poisonous chemicals.

When applied to the skin: Pomegranate extract is possibly safe. Some people might have allergic reactions.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Pomegranate fruit and fruit juice are possibly safe when used during pregnancy or when breast-feeding. But there isn't enough reliable information to know if other forms of pomegranate, such as pomegranate extract, are safe to use. Stay on the safe side and stick with pomegranate fruit or juice.

Allergies to plants: People with plant allergies seem to be more likely to have an allergic reaction to pomegranate.

Surgery: Pomegranate might affect blood pressure. This might interfere with blood pressure control during and after surgery. Stop taking pomegranate at least 2 weeks before a scheduled surgery.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Possibly effective Effectiveness definitions

High blood pressure. Drinking pomegranate juice daily can lower systolic blood pressure (the top number) by about 5 mmHg. But it doesn't seem to reduce diastolic pressure (the lower number).

Possibly ineffective Effectiveness definitions

Diabetes. Taking pomegranate by mouth doesn't improve blood sugar in people with diabetes.
High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Taking pomegranate by mouth doesn't seem to lower cholesterol in people with or without high cholesterol.

There is interest in using pomegranate for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Dosing & administration

Pomegranate juice has most often been used by adults in doses of 50-240 mL by mouth daily for up to 3 months. Pomegranate fruit extract has been used in doses of up to 3 grams by mouth daily for up to 18 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

Carbamazepine (Tegretol)

Interaction Rating=Minor Be watchful with this combination.

Carbamazepine is broken down by the body. Taking pomegranate might decrease how quickly the body breaks down carbamazepine. This might increase the effects and side effects of carbamazepine.

Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates)

Interaction Rating=Minor Be watchful with this combination.

Some medications are changed and broken down by the liver. Pomegranate might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.