Tocotrienols
Tocotrienols

Background

Vitamin E is an essential nutrient that includes both tocotrienols and tocopherols. Tocotrienols have double bonds and are found in palm and rice bran oil.

Tocotrienols exist in four different forms: alpha-, beta-, gamma-, and delta-tocotrienols. Tocotrienols seem to have many different effects in the body. They might lower cholesterol levels and provide heart health benefits.

People use tocotrienols for high cholesterol, cancer, stroke, aging, and many other conditions, but there is no good scientific evidence to support these uses.

To learn about tocopherols, another source of vitamin E, review vitamin E.
When taken by mouth: Tocotrienols are possibly safe when used at a dose of 200 mg daily for up to 5 years. They're usually well tolerated.

When applied to the skin: There isn't enough reliable information to know if tocotrienols are safe. Tocotrienol cream can cause mild itching in some people.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if tocotrienols are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Diabetes. Taking tocotrienols by mouth may improve blood sugar in adults with type 2 diabetes.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
  • High cholesterol. Taking tocotrienols by mouth doesn't seem to improve cholesterol levels.
There is interest in using tocotrienols for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Insufficient evidence Effectiveness definitions

Dosing & administration

Tocotrienols have most often been used by adults in doses of 200-600 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)

Interaction Rating=Minor Be watchful with this combination.

Tocotrienols might slow blood clotting. Taking tocotrienols along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 17/10/2023 11:00:00 and last updated on 15/05/2022 07:29:59. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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