Tocotrienols
Scientific names: Alpha-Tocotrienol, Beta-TocotrienolDelta-TocotrienolGamma-Tocotrienol
Alternative names: 8-Methyltocotrienol, Alpha Tocotrienol, Alpha-Tocotriénol, Beta Tocotrienol, Bêta-Tocotriénol, Concentré de Tocotriénol, D-Alpha Tocotrienol, D-Alpha Tocotriénol, D-Gamma Tocotrienol, D-Gamma-Tocotriénol, Delta Tocotrienol, Delta-Tocotriénol, Epsilon-Tocopherol, Epsilon-Tokoferol, Epsilon Tocopherol, Gamma Tocotrienol, Gamma-Tocotriénol, Mixed Tocotrienols, Palm Tocotrienols, Rice Tocotrienols, Tocotrienol, Tocotriénol, Tocotrienol Concentrate, Tocotriénols, Tocotriénols de Palme, Tocotriénols de Riz, Tocotriénols Mixtes, Zeta1-Tocopherol
Actions: Antiaging, Anticancer, Antioxidant activity, Autonomic, Cardiovascular, CYP450, Hypolipidemic, Neuroprotective
Background
Vitamin E is an essential nutrient that includes both tocotrienols and tocopherols. Tocotrienols have double bonds and are found in palm and rice bran oil.
Tocotrienols exist in four different forms: alpha-, beta-, gamma-, and delta-tocotrienols. Tocotrienols seem to have many different effects in the body. They might lower cholesterol levels and provide heart health benefits.
People use tocotrienols for high cholesterol, cancer, stroke, aging, and many other conditions, but there is no good scientific evidence to support these uses.
To learn about tocopherols, another source of vitamin E, review vitamin E.
Tocotrienols exist in four different forms: alpha-, beta-, gamma-, and delta-tocotrienols. Tocotrienols seem to have many different effects in the body. They might lower cholesterol levels and provide heart health benefits.
People use tocotrienols for high cholesterol, cancer, stroke, aging, and many other conditions, but there is no good scientific evidence to support these uses.
To learn about tocopherols, another source of vitamin E, review vitamin E.
Safety Safety definitions
When taken by mouth: Tocotrienols are possibly safe when used at a dose of 200 mg daily for up to 5 years. They're usually well tolerated.
When applied to the skin: There isn't enough reliable information to know if tocotrienols are safe. Tocotrienol cream can cause mild itching in some people.
When applied to the skin: There isn't enough reliable information to know if tocotrienols are safe. Tocotrienol cream can cause mild itching in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if tocotrienols are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Diabetes. Taking tocotrienols by mouth may improve blood sugar in adults with type 2 diabetes.
Possibly ineffective Effectiveness definitions
- High cholesterol. Taking tocotrienols by mouth doesn't seem to improve cholesterol levels.
Dosing & administration
Tocotrienols have most often been used by adults in doses of 200-600 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Minor Be watchful with this combination.
Tocotrienols might slow blood clotting. Taking tocotrienols along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
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Per capsule:
- Tocopherols concentrate - mixed (high-alpha type) (Vitamin E) 37.8 mg equiv. d-alpha-tocopherol 36.2 mg
- Tocopherols concentrate - mixed (low-alpha type) (Vitamin E) 82.7 mg equiv. d-alpha tocopherol 30.7 mg
- Tocotrienols complex - palm (Vitamin E) 19.9 mg equiv. d-alpha tocopherol 6.7 mg equiv. mixed tocotrienols 5.9 mg
- Bixa orellana ext. 32.5 mg
- Selenomethionine 123.4 µg equiv. selenium 50 µg
- Haematococcus pluvialis (Chlorophyll) 20 mg equiv. natural astaxanthin 2 mg
Practitioner product
Per tablet:
- Tocopherols concentrate - mixed (low-alpha type) 12 mg
- d-alpha-Tocopheryl acid succinate 123 mg equiv. vitamin E 149 IU
- Ascorbic acid (Vitamin C) 100 mg
- Cholecalciferol 25 μg equiv. vitamin D3 1000 IU
- Co-methylcobalamin (Vitamin B12) 400 μg
- Zinc bisglycinate (Zinc amino acid chelate) 50 mg equiv. zinc 10 mg
- Vitis vinifera ext. 158 mg
- Camellia sinensis ext. 120 mg
- Beta-carotene carotenoids (Vitamin A) 6 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Riboflavin (Vitamin B2) 20 mg
- Nicotinamide (Vitamin B3) 100 mg
- Calcium pantothenate (Vitamin B5) 50 mg
- Pyridoxal 5-phosphate (P5P) 5 mg
- Pyridoxine hydrochloride (Vitamin B6) 30 mg
- Calcium folinate (Activated folate) 433 μg equiv. folinic acid 400 μg
- Biotin 50 μg
- Borax 26 mg equiv. boron 3 mg
- Manganese amino acid chelate 16 mg equiv. manganese 2.5 mg
- Chromic chloride 769 μg equiv. chromium 150 μg
- Molybdenum trioxide 188 μg equiv. molybdenum 125 μg
- Selenomethionine 188 μg equiv. selenium 75 μg
- Potassium iodide 131 μg equiv. iodine 100 μg
Practitioner product
Per tablet:
- d-alpha-Tocopheryl acid succinate 82.64 mg equiv. vitamin E 100 IU
- Tocopherols concentrate - mixed (low-alpha type) 14.7 mg
- Ascorbic acid (Vitamin C) 100 mg
- Retinol acetate 431.2 μg equiv. vitamin A 375 μgRE
- Cyanocobalamin (Vitamin B12) 400 μg
- Cholecalciferol 2.5 μg equiv. vitamin D3 100 IU
- Zinc amino acid chelate 50 mg equiv. zinc 10 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Riboflavin (Vitamin B2) 50 mg
- Nicotinamide (Vitamin B3) 200 mg
- Calcium pantothenate (Vitamin B5) 100 mg equiv. pantothenic acid 91.6 mg equiv. calcium 8.39 mg
- Pyridoxine hydrochloride (Vitamin B6) 50 mg equiv. pyridoxine 41.14 mg
- Folic acid 400 μg
- Biotin 100 μg
- Phytomenadione (Vitamin K1) 30 μg
- Borax 8.82 mg equiv. boron 1 mg
- Calcium citrate 237 mg equiv. calcium 50 mg
- Chromium nicotinate 416.67 μg equiv. chromium 50 μg
- Copper gluconate 1.43 mg equiv. copper 200 μg
- Magnesium oxide - heavy 41.46 mg equiv. magnesium 25 mg
- Manganese amino acid chelate 5 mg equiv. manganese 1 mg
- Molybdenum trioxide 113 μg equiv. molybdenum 75 μg
- Selenomethionine 64.58 μg equiv. selenium 26 μg
- Citrus bioflavonoids extract 50 mg
- Choline bitartrate 50 mg equiv. choline 20 mg
- Myo-inositol 50 mg
- Beta-carotene carotenoids (Vitamin A) 4 mg
Practitioner product
Per capsule:
- d-alpha-Tocopheryl acid succinate 82.64 mg equiv. vitamin E 100 IU
- Tocopherols concentrate - mixed (low-alpha type) 5 mg
- Reynoutria japonica ext. 50 mg
- Vitis vinifera ext. 4.167 mg
- Ginkgo biloba ext. 6 mg
- Curcuma longa ext. 30 mg
- Vaccinium myrtillus ext. 1 mg
- Ascorbic acid (Vitamin C) 120 mg
- Silybum marianum ext. 11.43 mg
- Camellia sinensis ext. 50 mg
- Rutin (Rutoside) 100 mg
- Selenomethionine 125 μg equiv. selenium 50 μg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Glycine 50 mg
- Cysteine hydrochloride monohydrate 50 mg
- Glutamine 50 mg
- Zinc citrate dihydrate 15.58 mg equiv. zinc 5 mg
Practitioner product
Per tablet:
- d-alpha-Tocopheryl acid succinate 41.3 mg equiv. vitamin E 50 IU
- Tocopherols concentrate - mixed (low-alpha type) 20 mg
- Reynoutria japonica ext. 20 mg
- Asparagus racemosus ext. 70.58 mg
- Vitex agnus-castus ext. 25 mg
- Retinol acetate 354 μg equiv. vitamin A 300 μg RE
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Riboflavin (Vitamin B2) 30 mg
- Nicotinamide (Vitamin B3) 50 mg
- Calcium pantothenate (Vitamin B5) 50 mg equiv. pantothenic acid 45.8 mg
- Cyanocobalamin (Vitamin B12) 150 μg
- Folic acid 500 μg
- Ascorbic acid (Vitamin C) 100 mg
- Cholecalciferol 25 μg equiv. vitamin D3 1000 IU
- Biotin 150 μg
- Phytomenadione (Vitamin K1) 30 μg
- Choline bitartrate 25 mg
- Inositol 25 mg
- Calcium hydrogen phosphate dihydrate 258.2 mg equiv. calcium 60 mg equiv. phosphorous 46.47 mg
- Magnesium amino acid chelate 150 mg equiv. magnesium 30 mg
- Iron amino acid chelate 50 mg equiv. iron 5 mg
- Borax 26.5 mg equiv. boron 3 mg
- Zinc amino acid chelate 25 mg equiv. zinc 5 mg
- Manganese amino acid chelate 20 mg equiv. manganese 2 mg
- Chromium chloride hexahydrate 1.28 mg equiv. chromium 250 μg
- Potassium iodide (Iodine) 391 μg equiv. iodine 299 μg equiv. potassium 92 μg
- Molybdenum trioxide 150 μg equiv. molybdenum 100 μg
- Selenomethionine 124.2 μg equiv. selenium 50 μg
- Pyridoxine hydrochloride (Vitamin B6) 50 mg equiv. pyridoxine 41 mg
Practitioner product
Per tablet:
- d-alpha-Tocopheryl acid succinate 28 mg equiv. vitamin E 34 IU
- Tocopherols concentrate - mixed (low-alpha type) 13.5 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg equiv. thiamine 44.6 mg
- Nicotinamide (Vitamin B3) 220 mg
- Pyridoxine hydrochloride (Vitamin B6) 48.62 mg equiv. pyridoxine 40 mg
- Riboflavin 5-phosphate sodium (Activated B2) 27.4 mg equiv. riboflavin 20 mg
- Mecobalamin (Vitamin B12) 500 μg
- Selenomethionine 65 μg equiv. selenium 26 μg
- Retinol acetate 884 μg equiv. vitamin A 750 μg RE
- Nicotinic acid (Vitamin B3) 5 mg
- Calcium pantothenate (Vitamin B5) 100 mg equiv. pantothenic acid 91.6 mg equiv. calcium 8.4 mg
- Calcium folinate (Activated folate) 278 μg equiv. folinic acid 200 μg
- Levomefolate calcium (Activated folate) 216 μg equiv. levomefolic acid 200 μg
- Calcium ascorbate dihydrate (Vitamin C) 121.7 mg equiv. ascorbic acid 100 mg equiv. calcium 11.44 mg
- Cholecalciferol 2.5 μg equiv. vitamin D3 100 IU
- R,S-alpha lipoic acid 10 mg
- Biotin 150 μg
- Ananas comosus (Bromelain) 6 mg
- Choline bitartrate 40 mg
- Cysteine hydrochloride monohydrate 21.74 mg equiv. cysteine 15 mg
- L-glutamine 40 mg
- Citrus bioflavonoids extract 5 mg
- Inositol 25 mg
- Lecithin 15 mg
- Rutin (Rutoside) 10 mg
- Taurine 85 mg
- Chromium nicotinate 205 μg equiv. chromium 25 μg
- Potassium iodide (Iodine) 41 μg equiv. iodine 31 μg equiv. potassium 9.6 μg
- Magnesium phosphate pentahydrate 50 mg equiv. magnesium 10 mg
- Manganese amino acid chelate 250 μg equiv. manganese 50 μg
- Potassium phosphate dibasic 31.82 mg equiv. potassium 14 mg
- Zinc amino acid chelate 72 mg equiv. zinc 14.4 mg
- Molybdenum trioxide 75 μg equiv. molybdenum 50 μg
- Rosa canina ext. 10 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 10 mg equiv. pyridoxine 6.38 mg
- Citrus bioflavonoids extract 5 mg
- Lysine hydrochloride 35 mg equiv. lysine 27.45 mg
- Copper gluconate 43 μg equiv. copper 6 μg
Practitioner product
Per tablet:
- d-alpha-Tocopheryl acid succinate (Vitamin E) 25 mg equiv. d-alpha-tocopherol 20 mg
- Tocopherols concentrate - mixed (low-alpha type) 2.5 mg
- Ascorbic acid (Vitamin C) 50 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- Co-methylcobalamin (Vitamin B12) 400 μg
- Zinc sulphate monohydrate 28 mg equiv. zinc 10 mg
- Beta-carotene carotenoids (Vitamin A) 4 mg
- Phytomenadione (Vitamin K1) 80 μg
- Nicotinamide (Vitamin B3) 100 mg
- Calcium pantothenate (Vitamin B5) 50 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Pyridoxine hydrochloride (Vitamin B6) 40 mg
- Riboflavin (Vitamin B2) 20 mg
- Pyridoxal 5-phosphate (P5P) 5 mg
- Folic acid 400 μg
- Biotin 50 μg
- Calcium citrate tetrahydrate 190 mg equiv. calcium 40 mg
- Calcium hydrogen phosphate dihydrate 172 mg equiv. calcium 40 mg
- Calcium amino acid chelate 100 mg equiv. calcium 20 mg
- Potassium phosphate dibasic 78 mg equiv. potassium 35 mg
- Magnesium oxide - heavy 66 mg equiv. magnesium 40 mg
- Borax 27 mg equiv. boron 3 mg
- Manganese amino acid chelate 16 mg equiv. manganese 2.5 mg
- Chromic chloride hexahydrate 769 μg equiv. chromium 150 μg
- Potassium iodide 391 μg equiv. iodine 299 μg
- Molybdenum trioxide 150 μg equiv. molybdenum 100 μg
- Selenomethionine 65 μg equiv. selenium 26 μg
- Magnesium bisglycinate 100 mg equiv. magnesium 10 mg
- Iron bisglycinate 25 mg equiv. iron 5 mg
- Brassica oleracea var. italica powder 100 mg
Practitioner product
Per tablet:
- d-alpha-Tocopheryl acid succinate 25 mg equiv. vitamin E 20 mg
- Tocopherols concentrate - mixed (low-alpha type) 2.5 mg
- Ascorbic acid (Vitamin C) 50 mg
- Cholecalciferol 13 μg equiv. vitamin D3 500 IU
- Co-methylcobalamin (Vitamin B12) 400 μg
- Zinc sulphate monohydrate 55 mg equiv. zinc 20 mg
- Silybum marianum ext. 51 mg
- Phytomenadione (Vitamin K1) 80 μg
- Nicotinamide (Vitamin B3) 100 mg
- Calcium pantothenate (Vitamin B5) 50 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Pyridoxine hydrochloride (Vitamin B6) 30 mg
- Riboflavin (Vitamin B2) 20 mg
- Pyridoxal 5-phosphate (P5P) 5 mg
- Folic acid 400 μg
- Biotin 50 μg
- Calcium hydrogen phosphate dihydrate 258 mg equiv. calcium 60 mg
- Calcium citrate tetrahydrate 142 mg equiv. calcium 30 mg
- Magnesium amino acid chelate 100 mg equiv. magnesium 10 mg
- Potassium phosphate dibasic 78 mg equiv. potassium 35 mg
- Calcium amino acid chelate 50 mg equiv. calcium 10 mg
- Borax 27 mg equiv. boron 3 mg
- Manganese amino acid chelate 16 mg equiv. manganese 2.5 mg
- Chromium chloride hexahydrate 769 μg equiv. chromium 150 μg
- Molybdenum trioxide 188 μg equiv. molybdenum 125 μg
- Selenomethionine 65 μg equiv. selenium 26 μg
- Potassium iodide 52 μg equiv. iodine 40 μg
- Beta-carotene carotenoids (Vitamin A) 4 mg
Practitioner product
Practitioner product
Practitioner product
Practitioner product
Per 15 g (Rich Chocolate):
- d-alpha-Tocopheryl acid succinate (Vitamin E)
- Tocopherols concentrate - mixed (Vitamin E)
- Pea protein isolate 8.3 g
- Lactobacillus acidophilus 1.58 billion CFU
- Bifidobacterium bifidum 1.58 billion CFU
- Marine algae 500 mg
- Linum usitatissimum (seed) (Flaxseed) 250 mg
- Sunflower lecithin 200 mg
- Spinacia oleracea (Spinach) 100 mg
- Beta vulgaris (root) powder (Beetroot) 100 mg
- Daucus carota powder (Carrot) 100 mg
- Arthrospira platensis (Spirulina) 100 mg
- Wheatgrass powder 100 mg
- Zingiber officinale powder 40 mg
- Ribes nigrum powder 200 mg
- Vitis vinifera powder 200 mg
- Malpighia glabra powder 100 mg
- Lycium chinese powder 100 mg
- Vaccinium myrtillus powder 100 mg
- Bacopa monnieri powder 50 mg
- Taraxacum officinale powder 30 mg
- Malus (fibre) powder (Apple) 587 g
- Apple pectin 200 mg
- Plantago ovata (husk) (Psyllium) 100 mg
- Citric acid anhydrous 150 mg
- Citrus bioflavonoids extract 70 mg
- Ananas comosus (Bromelain) 30 mg
- R,S-alpha lipoic acid 20 mg
- Beta glucan 11.5 mg
- Dunaliella salina 8 mg
- Lutein 2 mg
- Zeaxanthin (Carotenoids) 400 µg
- Natural chocolate flavour
- Potassium phosphate dibasic
- Calcium citrate
- Ascorbic acid (Vitamin C)
- Zinc gluconate
- Thaumatin
- Nicotinamide (Vitamin B3)
- Manganese gluconate
- D-calcium pantothenate (Vitamin B5)
- Selenomethionine
- Retinyl palmitate
- Riboflavin (Vitamin B2)
- Thiamine hydrochloride (Vitamin B1)
- Pyridoxine hydrochloride (Vitamin B6)
- Folate
- Chromium picolinate
- Cholecalciferol
- Fucus vesiculosus powder 97 mg
- Stevia rebaubiana powder
- Phytomenadione (Vitamin K1)
- Copper gluconate
- Calendula officinalis powder
- Biotin
- Cyanocobalamin (Vitamin B12)
- Theobroma cacao powder 2.1 g
- Brassica oleracea var. italica powder 100 mg
- Carica papaya 50 mg
- Hordeum vulgare 100 mg
- Natural vanilla flavour
- Magnesium gluconate
- Menaquinone 7 (Vitamin K2)
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Per 3.1 g (Lime):
- d-alpha-Tocopheryl acid succinate 200 mg equiv. vitamin E 242 IU
- Quercetin dihydrate 447.7 mg equiv. quercetin 400 mg
- Rutin (Rutoside) 500 mg
- Ananas comosus (Bromelain) 1.5 million PU
- Magnesium ascorbate monohydrate (Vitamin C) 952.7 mg equiv. ascorbic acid 850 mg
- Zinc gluconate 27.93 mg equiv. zinc 4 mg
- Calcium pantothenate (Vitamin B5) 109 mg equiv. pantothenic acid 99.9 mg
- Selenomethionine 32.24 μg equiv. selenium 13 μg
- Retinol acetate (Vitamin A) 0.884 mg equiv. vitamin A 750 μgRE equiv. vitamin A 2500 IU
Practitioner product
Practitioner product
Per tablet:
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Per capsule:
- d-alpha-Tocopheryl acid succinate 124 mg equiv. vitamin E 150 IU
- Ganoderma lucidum ext. 37.5 mg
- Lentinula edodes ext. 150 mg
- Trametes versicolor ext. 65 mg
- Curcuma longa 23.43 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- Selenomethionine 187.5 μg equiv. selenium 75 μg
- Zinc citrate dihydrate 23.44 mg equiv. zinc 7.5 mg
- Camellia sinensis ext. 166.7 mg
- Retinol palmitate (Vitamin A) 2 mg equiv. vitamin A 3650 IU equiv. vitamin A 1096 μg RE
Practitioner product
Per tablet:
- d-alpha-Tocopheryl acid succinate 110 mg equiv. vitamin E 134 IU
- Withania somnifera ext. 60 mg
- Selenomethionine 94 μg equiv. selenium 37.5 μg
- Potassium iodide 92 μg equiv. iodine 70 μg
- Lycium barbarum ext. 300 mg
- Zingiber officinale ext. 25 mg
- Rosmarinus officinalis ext. 50 mg
- Nicotinamide (Vitamin B3) 100 mg
- Zinc sulphate monohydrate 16.5 mg equiv. zinc 6 mg
- Riboflavin (Vitamin B2) 5 mg
- Retinyl palmitate 240 μg equiv. vitamin A 130 μg RE
Practitioner product
Per capsule:
- d-alpha-Tocopheryl acid succinate (Vitamin E) 103.21 mg equiv. d-alpha-tocopherol 125 IU
- Viburnum opulus ext. 56.3 mg
- Angelica polymorpha ext. 28.15 mg
- Alchemilla vulgaris ext. 75 mg
- Corydalis turtschaninovii ext. 62.5 mg
- Matricaria chamomilla ext. 37.5 mg
- Zingiber officinale ext. 12.5 mg
- Thiamine hydrochloride (Vitamin B1) 31.78 mg equiv. thiamine 25 mg
Practitioner product
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This monograph was last reviewed on 03/10/2024 10:00:00 and last updated on 15/05/2022 07:29:59. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
