Lactiplantibacillus plantarum
Scientific names: Lactiplantibacillus plantarum
Family: Lactobacillaceae
Alternate names: L. plantarum, Lactobacillus Plantarum, Probiotic, Probiotique
Actions: General, Antibiotic adverse effect prevention, Cardiovascular, Chemotherapy protective, Gastrointestinal, Immunomodulating, Neurological
Background
Lactiplantibacillus plantarum (L. plantarum) is a type of probiotic ("good" bacteria) found in the mouth and gut. It's also found in fermented foods.
"Good" bacteria such as L. plantarum can help break down food, absorb nutrients, and fight off "bad" organisms that might cause diseases. Specific strains of L. plantarum are commonly added to fermented foods like yogurt and are also found in probiotic supplements.
People use L. plantarum for eczema, high cholesterol, irritable bowel syndrome (IBS), a type of inflammatory bowel disease (ulcerative colitis), and to prevent the common cold or other respiratory tract infections. It is also used for diarrhea, constipation, and many other conditions, but there is no good scientific evidence to support many of these other uses. There is also no good evidence to support using L. plantarum for COVID-19.
Don't confuse L. plantarum with other probiotics, or with fermented food products such as fermented milk, kefir, or yogurt. These are not the same. Also note that L. plantarum used to be classified under the Lactobacillus genus. But Lactobacillus was split up into 25 different genera in April 2020. Some product labels might still list this species as Lactobacillus plantarum rather than its new name, Lactiplantibacillus plantarum.
"Good" bacteria such as L. plantarum can help break down food, absorb nutrients, and fight off "bad" organisms that might cause diseases. Specific strains of L. plantarum are commonly added to fermented foods like yogurt and are also found in probiotic supplements.
People use L. plantarum for eczema, high cholesterol, irritable bowel syndrome (IBS), a type of inflammatory bowel disease (ulcerative colitis), and to prevent the common cold or other respiratory tract infections. It is also used for diarrhea, constipation, and many other conditions, but there is no good scientific evidence to support many of these other uses. There is also no good evidence to support using L. plantarum for COVID-19.
Don't confuse L. plantarum with other probiotics, or with fermented food products such as fermented milk, kefir, or yogurt. These are not the same. Also note that L. plantarum used to be classified under the Lactobacillus genus. But Lactobacillus was split up into 25 different genera in April 2020. Some product labels might still list this species as Lactobacillus plantarum rather than its new name, Lactiplantibacillus plantarum.
Safety Safety definitions
When taken by mouth: Live L. plantarum is likely safe. It's been used safely together with other probiotics for up to 9 months. Some people might experience gas or bloating, but it's usually well-tolerated. Heat-killed L. plantarum is possibly safe when used for up to one year.
When applied to the vagina: L. plantarum is possibly safe.
Breast-feeding: There isn't enough reliable information to know if L. plantarum is safe to use while breast-feeding. But there's no reason to expect safety concerns when used appropriately under medical supervision.
Children: L. plantarum is likely safe when taken by mouth appropriately in most children. It's been used safely alone and together with other probiotics. However, there isn't enough reliable information to know if L. plantarum is safe for very small premature infants.
Weakened immune system: L. plantarum has caused blood infections in a small number of people with weakened immune systems. If you have a weakened immune system, talk with your healthcare provider before taking L. plantarum.
Damaged heart valves: L. plantarum can cause an infection in the inner lining of the heart chambers and heart valve. This is extremely rare, but people with damaged heart valves should stop taking probiotics before dental procedures or surgical procedures.
When applied to the vagina: L. plantarum is possibly safe.
Special Precautions & Warnings:
Pregnancy: L. plantarum is possibly safe when taken by mouth during pregnancy. It's been used safely starting at 10-12 weeks of pregnancy and continued until delivery.Breast-feeding: There isn't enough reliable information to know if L. plantarum is safe to use while breast-feeding. But there's no reason to expect safety concerns when used appropriately under medical supervision.
Children: L. plantarum is likely safe when taken by mouth appropriately in most children. It's been used safely alone and together with other probiotics. However, there isn't enough reliable information to know if L. plantarum is safe for very small premature infants.
Weakened immune system: L. plantarum has caused blood infections in a small number of people with weakened immune systems. If you have a weakened immune system, talk with your healthcare provider before taking L. plantarum.
Damaged heart valves: L. plantarum can cause an infection in the inner lining of the heart chambers and heart valve. This is extremely rare, but people with damaged heart valves should stop taking probiotics before dental procedures or surgical procedures.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Eczema (atopic dermatitis). Taking L. plantarum by mouth seems to help treat eczema in children and adults.
- Common cold. Taking L. plantarum by mouth with another probiotic called L. paracasei seems to help prevent the common cold.
- High cholesterol. Taking L. plantarum by mouth seems to help lower cholesterol by a small amount.
- A long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS). Taking L. plantarum by mouth, alone or with other probiotics, seems to help improve symptoms of IBS.
- Infection of the airways. Taking L. plantarum by mouth, alone or with other probiotics, seems to prevent airway infections in adults.
- A type of inflammatory bowel disease (ulcerative colitis). Taking L. plantarum by mouth together with standard treatment seems to increase remission and prevent relapse in people with ulcerative colitis.
Possibly ineffective Effectiveness definitions
- Diarrhea in people taking antibiotics (antibiotic-associated diarrhea). Taking L. plantarum alone by mouth doesn't seem to reduce the risk of diarrhea while taking antibiotics. There isn't enough reliable information to say whether taking L. plantarum with other probiotics would be helpful.
Dosing & administration
L. plantarum is sometimes added to fermented foods such as yogurts, but it's most commonly taken in dietary supplements.
In adults, L. plantarum has most often been taken by mouth, alone or together with other probiotics, in doses of 500 million to 20 billion colony-forming units (CFUs) daily, for up to 3 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
In adults, L. plantarum has most often been taken by mouth, alone or together with other probiotics, in doses of 500 million to 20 billion colony-forming units (CFUs) daily, for up to 3 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Antibiotic drugs
Interaction Rating=Moderate Be cautious with this combination.
L. plantarum is a type of friendly bacteria. Antibiotics are used to reduce harmful bacteria in the body. Taking antibiotics along with L. plantarum can reduce the effects of L. plantarum. To avoid this interaction, take L. plantarum products at least 2 hours before or after antibiotics.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
View all productsPer 5 g:
- Lactobacillus plantarum (LP-115) 30 billion CFU
- Lactobacillus paracasei (LPC-37) 50 billion CFU
- Bifidobacterium bifidum (BB-06) 5 billion CFU
- Bifidobacterium animalis ssp. lactis (BI-04) 220 billion CFU
- Bifidobacterium animalis ssp. lactis (HN019) 35 billion CFU
- Bifidobacterium longum (BL-05) 5 billion CFU
- Lactobacillus acidophilus (LA-14) 50 billion CFU
- Lactobacillus brevis (LBR-35) 15 billion CFU
- Lactobacillus casei (LC-11) 10 billion CFU
- Lactobacillus gasseri (LG-36) 15 billion CFU
- Lactobacillus rhamnosus (HN001) 10 billion CFU
- Lactobacillus rhamnosus (LR-32) 5 billion CFU
- Lactobacillus salivarius (LS-33) 40 billion CFU
- Streptococcus thermophilus (ST-21) 10 billion CFU
Practitioner product
Practitioner product
Per capsule:
- Lactobacillus plantarum LP-115 (ATCC SD 5209) 20 billion CFU
- Lactobacillus rhamnosus GG (ATCC 53103) 35 billion CFU
- Lactobacillus gasseri LG-36 (ATCC SD 5585) 3 billion CFU
- Bifidobacterium animalis ssp. lactis (BL-12) (ATCC 27536) 10 billion CFU
- Bifidobacterium breve M-16V (LMG 23729) 3 billion CFU
- Bifidobacterium longum BB536 (ATCC BAA-999) 1 billion CFU
- Lactobacillus paracasei LPC-37 (ATCC SD 5275) 18 billion CFU
- Lactobacillus acidophilus LA-14 (ATCC SD 5212) 10 billion CFU
Practitioner product
Practitioner product
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RRP: $51.95$35.33Save: 32%
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RRP: $62.95$42.81Save: 32%
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Practitioner product
RRP: $50.95$34.65Save: 32%
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Practitioner product
RRP: $50.95$34.65Save: 32%
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Per capsule:
- Lactobacillus plantarum (LP-115) 8 billion CFU
- Lactobacillus casei (LC-11) 5 billion CFU
- Bifidobacterium animalis ssp. lactis (BI-04) 3 billion CFU
- Streptococcus thermophilus (ST-21) 1 billion CFU
- Lactobacillus paracasei (LPC-37) 6 billion CFU
- Lactobacillus acidophilus (LA-14) 3 billion CFU
- Lactobacillus gasseri (LG-36) 1.5 billion CFU
- Lactobacillus rhamnosus (LR-32) 1.5 billion CFU
- Bifidobacterium longum (BL-05) 500 million CFU
- Bifidobacterium breve (BB-18) 1 billion CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum 7.5 billion CFU
- Lactobacillus rhamnosus 9 billion CFU
- Lactobacillus acidophilus 7.5 billion CFU
- Lactobacillus casei 7.5 billion CFU
- Bifidobacterium lactis 4.5 billion CFU
- Bifidobacterium longum 4.5 billion CFU
- Lactobacillus salivarius 3 billion CFU
- Streptococcus thermophilus 1.5 billion CFU
Practitioner product
Per 3 g:
- Lactobacillus plantarum 7.5 billion CFU
- Lactobacillus rhamnosus 9 billion CFU
- Lactobacillus acidophilus 7.5 billion CFU
- Lactobacillus casei 7.5 billion CFU
- Bifidobacterium lactis 4.5 billion CFU
- Bifidobacterium longum 4.5 billion CFU
- Lactobacillus salivarius 3 billion CFU
- Streptococcus thermophilus (ST-21) 1.5 billion CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum (LP-115) 7 billion CFU
- Lactobacillus rhamnosus (HN001) 3 billion CFU
- Bifidobacterium animalis ssp. lactis (BS-01) 18 billion CFU
- Lactobacillus acidophilus (LA-14) 6 billion CFU
- Lactobacillus salivarius (LS-33) 3 billion CFU
- Lactobacillus paracasei (LPC-37) 3 billion CFU
- Bifidobacterium bifidum (BB-06) 1 billion CFU
- Bifidobacterium longum (BL-05) 1 billion CFU
- Bifidobacterium breve (BB-18) 4 billion CFU
- Lactobacillus casei (LC-11) 4 billion CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum (LP-115) 5 billion CFU
- Lactobacillus rhamnosus (HN001) 5 billion CFU
- Bifidobacterium animalis ssp. lactis (BI-04) 3 billion CFU
- Lactobacillus acidophilus (LA-14) 5 billion CFU
- Lactobacillus casei (LC-11) 500 million CFU
- Lactobacillus gasseri (LG-36) 100 million CFU
- Streptococcus thermophilus (ST-21) 500 million CFU
- Bifidobacterium longum (BL-05) 3 billion CFU
- Bifidobacterium breve (BB-18) 2 billion CFU
- Lactobacillus salivarius (LS-33) 400 million CFU
- Bifidobacterium infantis (BI-26) 400 million CFU
- Lactobacillus delbrueckii ssp. bulgaricus (LB-87) lactis 100 million CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum (LP01) 5 billion CFU
- Lactobacillus rhamnosus GG 20 billion CFU
- Lactobacillus casei (LC 03) 8 billion CFU
- Lactobacillus acidophilus (LA-14) 7 billion CFU
- Lactobacillus gasseri (LG-36) 2 billion CFU
- Bifidobacterium animalis ssp. lactis (BB-12) 5 billion CFU
- Bifidobacterium breve (BB-23) 2 billion CFU
- Bifidobacterium longum (BL-05) 1 million CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum (CCFM1143) 4 billion CFU
- Lactobacillus plantarum (CCFM8610) 2 billion CFU
- Lactobacillus rhamnosus GG (ATCC 53103) 10 billion CFU
- Bifidobacterium animalis ssp. lactis (BL-12) (ATCC 27536) 5 billion CFU
- Lactobacillus gasseri (CCFM1201) 3 billion CFU
- Lactobacillus casei (CCFM1073) 2 billion CFU
- Lactobacillus reuteri (CCFM1040) 1 billion CFU
- Bifidobacterium breve (CCFM1025) 1 billion CFU
- Bifidobacterium infantis (CCFM687) 1 billion CFU
- Bifidobacterium longum (CCFM1029) 1 billion CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum (CUL 66) 3.2 billion CFU
- Lactobacillus acidophilus (CUL 21 + CUL 60) 7.4 billion CFU
- Bifidobacterium animalis ssp. lactis (CUL 34) 4.3 billion CFU
- Bifidobacterium bifidum (CUL 20) 225 million CFU
- Lactobacillus rhamnosus (CUL 63) 15.6 billion CFU
- Lactobacillus casei (CUL 06) 9.5 billion CFU
- Lactobacillus fermentum (CUL 67) 1.4 billion CFU
- Streptococcus thermophilus (CUL 68) 2.3 billion CFU
- Bifidobacterium breve (BB-18) 1.4 billion CFU
Practitioner product
Per capsule:
- Lactobacillus plantarum (CUL 66) 3.15 billion CFU
- Lactobacillus acidophilus (CUL 21 + CUL 60) 20 billion CFU
- Bifidobacterium animalis ssp. lactis (CUL 34) 6.55 billion CFU
- Bifidobacterium bifidum (CUL 20) 345 million CFU
- Lactobacillus rhamnosus (CUL 63) 15.55 billion CFU
- Lactobacillus casei (CUL 06) 9.45 billion CFU
- Lactobacillus fermentum (CUL 67) 1.35 billion CFU
- Streptococcus thermophilus (CUL 68) 2.25 billion CFU
- Bifidobacterium breve (BB-18) 1.35 billion CFU
Practitioner product
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This monograph was last reviewed on 19/02/2024 11:00:00 and last updated on 08/06/2022 08:39:48. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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