Threonine
Scientific names: L-threonine
Alternate names: L-thréonine, Thréonine, Treonina
Actions: Lipotropic, Neurological
Background
Threonine is an essential amino acid. Amino acids are the building blocks of proteins. It cannot be made by the body and must be consumed in foods.
Threonine is changed in the body to a chemical called glycine. Glycine has effects in the brain that might reduce unwanted muscle contractions called spasticity.
People use threonine for Lou Gehrig's disease (amyotrophic lateral sclerosis or ALS), multiple sclerosis (MS), and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse threonine with another amino acid called theanine. These are not the same.
Threonine is changed in the body to a chemical called glycine. Glycine has effects in the brain that might reduce unwanted muscle contractions called spasticity.
People use threonine for Lou Gehrig's disease (amyotrophic lateral sclerosis or ALS), multiple sclerosis (MS), and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse threonine with another amino acid called theanine. These are not the same.
Safety Safety definitions
When taken by mouth: Threonine is commonly consumed in foods. People need about 0.5-1 gram of threonine from their diet daily. This amount is considered safe. Threonine is possibly safe when used in larger amounts as a medicine. Doses of up to 4 grams daily have been used safely for up to 12 months. It seems to be well-tolerated. Side effects might include stomach upset, headache, nausea, and skin rash.
Amyotrophic lateral sclerosis (Lou Gehrig's disease): There is some concern that threonine might decrease lung function in people with ALS. Talk to your healthcare provider before taking threonine if you have ALS.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Threonine is commonly consumed in foods. But as medicine, there isn't enough reliable information to know if threonine is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.Amyotrophic lateral sclerosis (Lou Gehrig's disease): There is some concern that threonine might decrease lung function in people with ALS. Talk to your healthcare provider before taking threonine if you have ALS.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly ineffective Effectiveness definitions
- Lou Gehrig's disease (amyotrophic lateral sclerosis or ALS). Taking threonine by mouth does not seem to slow the progression of ALS or reduce symptoms.
Dosing & administration
Threonine has most often been used by adults in doses of 1.5-2.5 grams by mouth three times daily for up to 8 weeks. A dose of up to 4 grams daily has been used for up to 12 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Medications for Alzheimer disease (NMDA antagonists)
Interaction Rating=Major Do not take this combination.
Threonine might decrease the effects of medications for Alzheimer disease.
Interactions with herbs & supplements
Alanine: Threonine might compete with other amino acids such as alanine to gain access to the central nervous system (CNS). Taking alanine with threonine might decrease the effectiveness of threonine.
Branched-chain amino acids: Threonine might compete with other amino acids such as branched-chain amino acids to gain access to the central nervous system (CNS). Taking branched-chain amino acids with threonine might decrease the effectiveness of threonine.
Phenylalanine: Threonine might compete with other amino acids such as phenylalanine to gain access to the central nervous system (CNS). Taking phenylalanine with threonine might decrease the effectiveness of threonine.
Serine: Threonine might compete with other amino acids such as serine to gain access to the central nervous system (CNS). Taking serine with threonine might decrease the effectiveness of threonine.
Tryptophan: Threonine might compete with other amino acids such as tryptophan to gain access to the central nervous system (CNS). Taking tryptophan with threonine might decrease the effectiveness of threonine.
Tyrosine: Threonine might compete with other amino acids such as tyrosine to gain access to the central nervous system (CNS). Taking tyrosine with threonine might decrease the effectiveness of threonine.
Branched-chain amino acids: Threonine might compete with other amino acids such as branched-chain amino acids to gain access to the central nervous system (CNS). Taking branched-chain amino acids with threonine might decrease the effectiveness of threonine.
Phenylalanine: Threonine might compete with other amino acids such as phenylalanine to gain access to the central nervous system (CNS). Taking phenylalanine with threonine might decrease the effectiveness of threonine.
Serine: Threonine might compete with other amino acids such as serine to gain access to the central nervous system (CNS). Taking serine with threonine might decrease the effectiveness of threonine.
Tryptophan: Threonine might compete with other amino acids such as tryptophan to gain access to the central nervous system (CNS). Taking tryptophan with threonine might decrease the effectiveness of threonine.
Tyrosine: Threonine might compete with other amino acids such as tyrosine to gain access to the central nervous system (CNS). Taking tyrosine with threonine might decrease the effectiveness of threonine.
Interactions with foods
There are no known interactions with foods.
Products
View all productsPer 6 g (Berry):
- L-threonine 1 g
- L-glutamine 1 g
- N-acetyl glucosamine (NAG) 1.5 g
- L-proline 750 mg
- L-serine 750 mg
- Beta vulgaris (root) powder (Beetroot)
- Citric acid anhydrous
- Malic acid
- Natural strawberry flavour
- Fragaria ananassa (juice) powder (Strawberry)
- Euterpe oleracea (berry) ext. (Acai)
- Aristotelia chilensis (Maqui berry)
- Garcinia mangostana juice dry
- Lycium chinese juice dry
- Glycine
- Silica - colloidal anhydrous
- Natural vanilla flavour
- Thaumatin
- Punica granatum
- Rubus idaeus
Practitioner product
Practitioner product
Per 37 g:
- L-threonine 200 mg
- Glutamine 2.22 g
- L-leucine 1.68 g
- Lysine hydrochloride 451.03 mg equiv. lysine 361 mg
- L-isoleucine 450 mg
- L-valine 450 mg
- L-phenylalanine 200 mg
- Cysteine hydrochloride 45 mg equiv. cysteine 31.04 mg
- L-methionine 120 mg
- L-tyrosine 112.5 mg
- Histidine hydrochloride 185.25 mg equiv. l-histidine 150 mg
- L-aspartic acid 111 mg
- L-proline 111 mg
- L-serine 27.75 mg
- Glycine 27.75 mg
- L-alanine 27.75 mg
- Taurine 11 mg
- Levocarnitine tartrate (L-carnitine) 10.99 mg equiv. levocarnitine 7.5 mg
- Potassium citrate 402.6 mg equiv. potassium 145.74 mg
- Magnesium citrate 167.09 mg equiv. magnesium 27 mg
- Magnesium glycerophosphate 49.99 mg equiv. magnesium 6.25 mg
- Calcium phosphate 62.64 mg equiv. calcium 25 mg
- Calcium glycerophosphate 393.27 mg equiv. calcium 75 mg
- Ferrous fumarate 45.6 mg equiv. iron 1.5 mg
- Manganese sulphate monohydrate 1.02 g equiv. manganese 330 µg
- Zinc sulphate monohydrate 5.74 mg equiv. zinc 2.08 mg
- Selenomethionine 28.64 µg equiv. selenium 11.54 µg
- Copper sulfate pentahydrate 656.27 µg equiv. copper 167 µg
- Molybdenum trioxide 12 µg equiv. molybdenum 8 µg
- Chromic chloride hexahydrate 46.95 µg equiv. chromium 9.16 µg
- Chromium picolinate 30.89 µg equiv. chromium 3.84 µg
- Potassium iodide 22.25 µg equiv. iodine 17 µg
- Borax 2.2 mg equiv. boron 250 µg
- Choline bitartrate 80.84 mg equiv. choline 33.25 mg
- Sodium ascorbate (Vitamin C) 22.5 mg equiv. ascorbic acid 20 mg
- dl-alpha-Tocopheryl acetate 10 mg equiv. vitamin E 10 IU
- Nicotinamide (Vitamin B3) 3.25 mg
- Retinol palmitate 418.58 µg equiv. vitamin A 767 IU
- Pyridoxine hydrochloride (Vitamin B6) 790 µg equiv. pyridoxine 650 µg
- Cholecalciferol 1.65 µg equiv. vitamin D3 66 IU
- Riboflavin (Vitamin B2) 500 µg
- Thiamine nitrate (Vitamin B1) 616.83 µg equiv. thiamine 500 µg
- Folic acid 31.27 µg
- Biotin 50 µg
- Calcium pantothenate (Vitamin B5) 3.53 mg equiv. pantothenic acid 3.25 mg
- Phytomenadione (Vitamin K1) 10 µg
- Cyanocobalamin (Vitamin B12) 2 µg
- Glucose monohydrate (Dextrose) 12.5 g
- Sunflower lecithin 250 mg
- Levomefolate glucosamine (Activated folate) 8 µg equiv. levomefolic acid 4.5 µg
- Medium Chain Triglycerides (powder) (MCT) 3 g
Practitioner product
Per 7 g (Lemonade):
- L-threonine
- Schisandra chinensis ext. equiv. dry 2.5 g
- L-leucine
- L-isoleucine
- L-methionine
- L-valine
- L-lysine
- L-phenylalanine
- L-histidine
- L-tryptophan
- Calcium citrate
- Magnesium bisglycinate
- Flavour
- Silica - colloidal anhydrous
- Ascorbic acid (Vitamin C)
- Potassium citrate
- Pyridoxal 5-phosphate (P5P)
- Methylcobalamin (Activated B12)
- Stevia rebaubiana
420 g Lemonade
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Per 12 g (Juicy Peach):
- Total Amino blend Amino9™ 2 g
- L-threonine
- L-leucine 2 g
- L-valine 1 g
- L-isoleucine 1 g
- L-histidine
- L-isoleucine
- L-leucine
- L-lysine
- L-methionine
- L-phenylalanine
- L-valine
- L-tryptophan
- L-glutamine 1 g
- Sodium chloride (Salt)
- Potassium chloride
- Calcium citrate
- Magnesium sulphate
- Ananas comosus (Bromelain) 25 mg
- Natural flavours
- Citric acid monohydrate
- Stevia rebaubiana
- Polyphenolic fulvic minerals 10 mg
- Tart cherry extract 250 mg
- Curcuma longa 50 mg
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Per 35 g (Chocolate Fudge):
- L-threonine
- Oryza sativa (Brown rice)
- Vicia faba (Fava bean protein)
- Pumpkin seed protein
- Cannabis sativa (seed)
- L-glutamine
- Acacia sp. (fibre)
- L-glycine
- L-valine
- L-leucine
- L-arginine
- L-isoleucine
- Theobroma cacao (Cocoa powder) 3.24 g
- Natural flavours
- Malus (powder) (Apple)
- Siraitia grosvenorii (Monk fruit)
- Medium Chain Triglycerides (powder) (MCT)
- Xanthan gum
- Eleutherococcus senticosus
- Coffea canephora
- Camellia sinensis
- Magnesium citrate
- Zinc gluconate
- Ferrous fumarate
- Pink Himalayan crystal salt
- Laminaria digitara (Kelp)
- Ananas comosus (Bromelain)
- Carica papaya (Papain)
- Vitamin D
- Cyanocobalamin (Vitamin B12)
RRP: $44.95$35.06Save: 22%
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Per 30 g (Passionfruit):
- L-threonine
- Hydrolysed pea protein
- L-alanine
- Glycine
- L-valine
- L-leucine
- L-isoleucine
- L-proline
- L-phenylalanine
- L-tyrosine
- L-serine
- L-methionine
- L-arginine
- L-histidine
- L-lysine
- L-aspartic acid
- L-glutamic acid
- L-tryptophan
- L-cysteine
- Natural flavours
- Cichorium intybus (root) (Chicory)
- Acacia sp. (gum)
- Coconut water powder
- Medium chain triglycerides (MCT)
- Potassium citrate
- Magnesium citrate
- Sodium chloride (Salt)
- Calcium citrate
- Ascorbic acid (Vitamin C)
- Citric acid anhydrous
- Stevia rebaubiana
- Thaumatin
- Beta-carotene
- Riboflavin (Vitamin B2)
$59.95
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Per 48 g:
- Whey protein concentrate
- Whey protein isolate
- Soy lecithin
- Theobroma cacao (Cocoa powder)
- Medium Chain Triglycerides (powder) (MCT)
- Calcium phosphate dibasic
- Flavour
- Magnesium citrate
- Cyamopsis tetragonoloba (Guar gum)
- Calcium citrate
- Zinc gluconate
- Ascorbic acid (Vitamin C)
- Beta-carotene carotenoids (Vitamin A)
- Chromium chloride
- Ferrous fumarate
- d-alpha-Tocopheryl acetate
- Calcium pantothenate (Vitamin B5)
- Riboflavin (Vitamin B2)
- Sodium selenite
- Thiamine hydrochloride (Vitamin B1)
- Cyanocobalamin (Vitamin B12)
- Biotin
- Potassium iodide
- Sodium molybdate
- Niacinamide (Vitamin B3)
- Copper sulfate
- Manganese citrate
- Cholecalciferol
- Folic acid
- Pyridoxine hydrochloride (Vitamin B6)
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Per 48 g:
- Whey protein concentrate
- Whey protein isolate
- Flavour
- Medium Chain Triglycerides (powder) (MCT)
- Calcium phosphate dibasic
- Magnesium citrate
- Cyamopsis tetragonoloba (Guar gum)
- Calcium citrate
- Zinc gluconate
- Ascorbic acid (Vitamin C)
- Beta-carotene carotenoids (Vitamin A)
- Chromium chloride
- Ferrous fumarate
- d-alpha-Tocopheryl acetate
- Niacinamide (Vitamin B3)
- Copper sulfate
- Magnesium citrate
- Cholecalciferol
- Folic acid
- Pyridoxine hydrochloride (Vitamin B6)
- Calcium pantothenate (Vitamin B5)
- Riboflavin (Vitamin B2)
- Sodium selenite
- Thiamine hydrochloride (Vitamin B1)
- Cyanocobalamin (Vitamin B12)
- Biotin
- Potassium iodide
- Sodium molybdate
- Soy lecithin
- Stevia rebaubiana
RRP: $64.96$58.47Save: 10%
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Per 30 g (Vanilla Bean):
1 kg Vanilla Bean
RRP: $85.95$70.91Save: 17%
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return unknown
RRP: $85.95$70.91Save: 17%
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Per 33 g (Banana Ice-Cream):
RRP: $79.99$70.39Save: 12%
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RRP: $49.95$43.96Save: 12%
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RRP: $58.95$48.63Save: 18%
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Per 30 g (Chocolate):
- Egg albumen powder
- Natural flavours
- Stevia rebaubiana
- Theobroma cacao
900 g Chocolate
RRP: $74.94$61.83Save: 17%
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1 kg Chocolate
RRP: $79.95$67.96Save: 15%
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Per 30 g (Cacao):
- Pea protein isolate 25.2 g
- Dunaliella salina equiv. beta-carotene 390 µg
- Aloe barbadensis 1 g
- Malpighia glabra equiv. vitamin C 50 mg
- d-alpha-Tocopheryl acid succinate 2.5 mg
- Natural chocolate flavour
- Stevia rebaubiana
- Thaumatin
- Luo Han Guo (fruit) ext. (Monk fruit)
RRP: $52.55$34.16Save: 35%
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RRP: $49.95$41.21Save: 17%
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RRP: $75.95$53.17Save: 30%
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