
Shark cartilage
Scientific names: Squalus acanthias, Sphyrna lewini
Alternative names: AE-941, Cartilage de Requin, Cartilage de Requin du Pacifique, Cartilago de Tiburon, Collagène Marin, Extrait de Cartilage de Requin, Liquide de Cartilage Marin, Marine Collagen, Marine Liquid Cartilage, MSI-1256F, Neovastat, Pacific Shark Cartilage, Poudre de Cartilage de Requin, Shark Cartilage Extract, Shark Cartilage Powder
Actions: Antiangiogenic, Antiarthritic, Anticancer, Anti-inflammatory, Antioxidant, Fibrinolytic, Immune stimulation, Media supplement
Background
Shark cartilage is the tissue that provides support for fins in sharks (Squalus acanthias). It mainly comes from sharks caught in the Pacific Ocean.
Shark cartilage became a popular medicine in the 1970s. But its popularity led to a decline in shark numbers. It was previously suggested that sharks don't get cancer, so consuming their cartilage might help prevent cancer in humans. But it is now clear that sharks do get cancer, and research hasn't shown benefits for cancer in humans.
People use shark cartilage for cancer, scaly itchy skin (psoriasis), osteoarthritis, and many other conditions, but there is no good scientific evidence supporting these uses.
Don't confuse shark cartilage with bovine cartilage, or with chondroitin, which can be sourced from shark cartilage.
Shark cartilage became a popular medicine in the 1970s. But its popularity led to a decline in shark numbers. It was previously suggested that sharks don't get cancer, so consuming their cartilage might help prevent cancer in humans. But it is now clear that sharks do get cancer, and research hasn't shown benefits for cancer in humans.
People use shark cartilage for cancer, scaly itchy skin (psoriasis), osteoarthritis, and many other conditions, but there is no good scientific evidence supporting these uses.
Don't confuse shark cartilage with bovine cartilage, or with chondroitin, which can be sourced from shark cartilage.
Safety Safety definitions
When taken by mouth: Shark cartilage is possibly safe when used for up to 40 months. It can cause a bad taste in the mouth, nausea, vomiting, stomach upset, and constipation.
When applied to the skin: Shark cartilage is possibly safe when used for up to 8 weeks.
"Autoimmune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Shark cartilage might cause the immune system to become more active. This could increase the symptoms of autoimmune diseases. If you have one of these conditions, it's best to avoid using shark cartilage.
High calcium levels (hypercalcemia): Shark cartilage contains calcium and might increase calcium levels. Do not use shark cartilage if you already have high calcium levels.
When applied to the skin: Shark cartilage is possibly safe when used for up to 8 weeks.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if shark cartilage is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use."Autoimmune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Shark cartilage might cause the immune system to become more active. This could increase the symptoms of autoimmune diseases. If you have one of these conditions, it's best to avoid using shark cartilage.
High calcium levels (hypercalcemia): Shark cartilage contains calcium and might increase calcium levels. Do not use shark cartilage if you already have high calcium levels.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely ineffective Effectiveness definitions
- Cancer. Taking shark cartilage by mouth does not benefit people with advanced, previously treated cancers, including breast, colon, lung, prostate, and brain cancer.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of shark cartilage might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
Medications that decrease the immune system (Immunosuppressants)
Interaction Rating=Moderate Be cautious with this combination.
Shark cartilage can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking shark cartilage along with these medications might decrease the effects of these medications.
Interactions with herbs & supplements
Calcium: Shark cartilage contains calcium and might raise calcium levels. Using it along with calcium supplements might make calcium levels too high.
Interactions with foods
Acidic fruit juices such as orange, apple, grape, or tomato, can lower the strength of shark cartilage. If shark cartilage is added to a fruit juice to improve flavor, it should be consumed right away.
Products
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Per tablet (Berry):
- Cholecalciferol 6.25 µg equiv. vitamin D3 250 IU
- d-alpha-Tocopherol 5 mg equiv. vitamin E 7.5 IU
- Co-methylcobalamin (Vitamin B12) 100 µg
- Zinc citrate 18.30 mg equiv. zinc 6.25 mg
- Calcium ascorbate (Vitamin C) 18.15 mg equiv. ascorbic acid 15 mg
- Phyllanthus emblica ext. 5 mg
- Menaquinone 7 (Vitamin K2) 20 µg
- Thiamine hydrochloride (Vitamin B1) 794 µg equiv. thiamine 625 µg
- Riboflavin 5-phosphate sodium (Activated B2) 855 µg equiv. riboflavin 625 µg
- Nicotinamide (Vitamin B3) 6.25 mg
- Calcium pantothenate (Vitamin B5) 2.98 mg equiv. pantothenic acid 2.5 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 1.01 mg equiv. pyridoxine 625 µg
- Levomefolate glucosamine (Activated folate) 370.37 µg equiv. levomefolic acid 200 µg
- Ferric pyrophosphate 5 mg
- Chromium picolinate 80.45 µg equiv. chromium 10 µg
- Copper sulfate pentahydrate 392.8 µg equiv. copper 100 µg
- Manganese gluconate 10.97 mg equiv. manganese 1.25 mg
- Selenomethionine 62.09 µg equiv. selenium 25 µg
- Borax 3.29 mg equiv. boron 375 µg
- Lutein 500 µg
- Lycopene 500 µg
- Lysine hydrochloride 3.12 mg equiv. lysine 2.5 mg
- Ascophyllum nodosum 9.34 mg
- Magnesium 6.25 mg
- Magnesium ascorbate (Vitamin C) 7.07 mg equiv. ascorbic acid 5 mg
- Calcified lithothamnion (Red algae) 13.22 mg equiv. calcium 4.17 mg
- Calcium ascorbate equiv. calcium 1.83 mg
- Calcium pantothenate equiv. calcium 0.25 mg
- Cruciferous vegetable blend 20 mg
- Ultra fruit blend 20 mg
- Live vegetable blend 20 mg
- Multi herb blend 20 mg
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Per capsule:
- Ganoderma lucidum ext. 76.8 mg
- Cordyceps sinensis ext. 76.8 mg
- Grifola frondosa ext. 76.8 mg
- Lentinula edodes ext. 76.8 mg
- Trametes versicolor ext. 76.8 mg
- Polyporus umbellatus ext. 38.4 mg
- Tremella fuciformis ext. 38.4 mg
- Poria cocos ext. 38.4 mg
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Per 10 g (Berry):
- Acacia sp. (gum) 2.5 g
- Cyamopsis tetragonoloba (Guar gum) 2 g
- Green banana starch 1.5 g
- Saccharomyces cerevisiae (boulardii) (SB) 5 billion CFU equiv. inactive (zinc powder) 24 mg
- L-glutamine 1.9 g
- Althaea officinalis ext. 500 mg
- Cinnamon zeylanicum powder 400 mg
- Protease
- Amylase enzyme
- Lipase
- Cellulase
- Lactase
- Berry flavour
- Bacillus coagulans 2 billion CFU
- Aloe barbadensis ext. 100 mg
- Punica granatum ext. 100 mg
- Natural vanilla flavour
- Malpighia glabra powder 50 mg
- Stevia rebaubiana powder 50 mg
- Beta vulgaris (root) powder (Beetroot) 33 mg
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Per tablet:
- Methylcobalamin (Activated B12) 200 μg
- Calcium ascorbate (Vitamin C) 30.25 mg equiv. ascorbic acid 25 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg
- Zinc citrate 200 mg equiv. zinc 36.6 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Thiamine hydrochloride (Vitamin B1) 1.59 mg equiv. thiamine 1.25 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Magnesium ascorbate (Vitamin C) 21.87 mg equiv. ascorbic acid 15.33 mg
- Levomefolate glucosamine (Activated folate) 463 μg equiv. levomefolic acid 250 μg
- Phyllanthus emblica ext. 9.35 mg
- Menaquinone 7 (Vitamin K2) 40 μg
- Calcified lithothamnion (Red algae) 31.52 mg equiv. calcium 9.46 mg
- Magnesium 12.5 mg
- Chromium picolinate 1.61 mg equiv. chromium 200 μg
- Copper sulfate 2 mg
- Ascophyllum nodosum 18.75 mg
- Manganese gluconate 21.93 mg equiv. manganese 2.5 mg
- Selenomethionine 124.18 μg equiv. selenium 50 μg
- Borax 6.6 mg equiv. boron 750 μg
- Lutein 1 mg
- Lycopene 1 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Curcumin (Turmeric) 500 μg
- Zingiber officinale ext. 5 mg
- Laminaria digitara (Kelp) 5 mg
- Citrus sinensis ext. 5 mg
- Cruciferous vegetable blend 25 mg
- Ultra fruit blend 25 mg
- Live vegetable blend 22.5 mg
- Multi herb blend 12.5 mg
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Per capsule:
- Nicotinamide mononucleotide (NMN) 500 mg
- Dimethylglycine hydrochloride (DMG) 250 mg
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Per tablet:
- Methylcobalamin (Activated B12) 200 μg
- Calcium ascorbate 30.25 mg equiv. calcium 3.04 mg equiv. ascorbic Acid 25 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg equiv. vitamin E 15 IU
- Zinc citrate 21.96 mg equiv. zinc 7.5 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Thiamine hydrochloride (Vitamin B1) 3.18 mg equiv. thiamine 2.5 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Levomefolate glucosamine (Activated folate) 463 μg equiv. levomefolic acid 250 μg
- Magnesium ascorbate (Vitamin C) 20.44 mg equiv. ascorbic acid 15.33 mg equiv. magnesium 2.19 mg
- Menaquinone 7 (Vitamin K2) 40 μg
- Calcified lithothamnion (Red algae) 73.19 mg equiv. calcium 21.96 mg
- Phyllanthus emblica ext. 9.35 mg
- Iron (II) glycinate 50 mg equiv. iron 10 mg
- Chromium picolinate 201.13 μg equiv. chromium 25 μg
- Cupric sulfate 2 mg equiv. copper 0.2 mg
- Manganese gluconate 10.97 mg equiv. manganese 1.25 mg
- Selenomethionine 124.18 μg equiv. selenium 50 μg
- Borax 6.58 mg equiv. boron 0.75 mg
- Lutein 1 mg
- Lycopene 1 mg
- Ascophyllum nodosum 18.75 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Zingiber officinale ext. 5 mg
- Laminaria digitara (Kelp) 5 mg
- Citrus sinensis ext. 5 mg
- Magnesium citrate 22.25 mg equiv. magnesium 3.61 mg
- Magnesium aspartate 25.49 mg equiv. magnesium 5.1 mg
- Cruciferous vegetable blend
- Ultra fruit blend
- Live vegetable blend
- Multi herb blend
- Curcumin (Turmeric) 500 μg
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Per tablet:
- Calcium ascorbate 60.49 mg equiv. calcium 6.088 mg equiv. ascorbic Acid 50 mg
- Cholecalciferol 12.5 µg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg equiv. vitamin E 15 IU
- Methylcobalamin (Activated B12) 200 µg
- Zinc citrate 21.96 mg equiv. zinc 7.5 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Magnesium ascorbate (Vitamin C) 38.92 mg equiv. ascorbic acid 27.827 mg equiv. magnesium 3.892 mg
- Phyllanthus emblica ext. 9.35 mg
- Menaquinone 7 (Vitamin K2) 40 µg
- Thiamine hydrochloride (Vitamin B1) 6.35 mg equiv. thiamine 5 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Levomefolate glucosamine (Activated folate) 463 µg equiv. levomefolic acid 250 µg
- Calcified lithothamnion (Red algae) 63.04 mg equiv. calcium 18.91 mg
- Magnesium 12.5 mg
- Chromium picolinate 201.13 µg equiv. chromium 25 µg
- Copper sulfate 200 µg
- Manganese gluconate 10.97 mg equiv. manganese 1.25 mg
- Selenomethionine 124.18 µg equiv. selenium 50 µg
- Borax 6.58 mg equiv. boron 750 µg
- Ascophyllum nodosum 18.75 mg
- Lutein 1 mg
- Lycopene 1 mg
- Alpha lipoic acid 25 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Curcumin (Turmeric) 500 μg
- Zingiber officinale ext. 5 mg
- Phyllanthus emblica ext. 10 mg
- Laminaria digitara (Kelp) 5 mg
- Ultra fruit blend 25 mg
- Cruciferous vegetable blend 25 mg
- Live vegetable blend 22.5 mg
- Multi herb blend 12.5 mg
- Citrus sinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
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Per tablet:
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg
- Methylcobalamin (Activated B12) 200 μg
- Zinc citrate 36.6 mg equiv. zinc 12.5 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Phyllanthus emblica ext. 65 mg
- Menaquinone 7 (Vitamin K2) 40 μg
- Thiamine hydrochloride (Vitamin B1) 6.35 mg equiv. thiamine 5 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Levomefolate glucosamine (Activated folate) 463 μg equiv. levomefolic acid 250 μg
- Calcified lithothamnion (Red algae) 28.72 mg equiv. calcium 8.62 mg
- Magnesium 13.13 mg
- Chromium picolinate 201.13 μg equiv. chromium 25 μg
- Copper sulfate 200 μg
- Manganese gluconate 43.86 mg equiv. manganese 5 mg
- Selenomethionine 124.18 μg equiv. selenium 50 μg
- Borax 6.6 mg equiv. boron 750 μg
- Ascophyllum nodosum 18.75 mg
- Lutein 1 mg
- Lycopene 1 mg
- Serenoa repens ext. 25 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Curcumin (Turmeric) 500 μg
- Zingiber officinale ext. 5 mg
- Laminaria digitara (Kelp) 5 mg
- Citrus sinensis ext. 5 mg
- Ultra fruit blend 25 mg
- Cruciferous vegetable blend 25 mg
- Live vegetable blend 22.5 mg
- Multi herb blend 12.5 mg
- Calcium ascorbate (Vitamin C) 38.58 mg equiv. ascorbic acid 32.5 mg equiv. calcium 3.88 mg
- Magnesium ascorbate (Vitamin C) 45.5 mg equiv. ascorbic acid 32.5 mg
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This monograph was last reviewed on 24/03/2025 11:00:00 and last updated on 16/09/2014 21:29:37. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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