Peony
Scientific names: Paeonia lactiflora, Paeonia albiflora, Paeonia mascula, Paeonia arietina, Paeonia caucasica, Paeonia corallina, Paeonia coriacea, Paeonia daurica, Paeonia kavachensis, Paeonia triternata, Paeonia obovata, Paeonia japonica, Paeonia obovata, Paeonia willmottiae, Paeonia officinalis, Paeonia microcarpa, Paeonia paradoxa, Paeonia suffruticosa, Paeonia arborea, Paeonia moutan, Paeonia anomala, Paeonia veitchii, Paeonia beresowskii, Paeonia woodwardii
Family: Ranunculaceae
Alternate names: Bai Shao, Chi Shao, Chinese Peony, Common Peony, Coral Peony, Cortex Moutan, European Peony, Jiu Chao Bai Shao, Moutan, Mu Dan Pi, Paeoniae Alba, Paeoniae Flos, Paeoniae Radix, Peonía, Peony Root, Piney, Pivoine, Pivoine Arbustive, Pivoine Blanche, Pivoine Commune, Pivoine de Chine, Pivoine des Jardins, Pivoine en Arbre, Pivoine Moutan, Pivoine Officinale, Pivoine Rouge, Racine de Pivoine, Radix Paeoniae, Radix Paeoniae Rubra, Radix Peony, Red Peony, Shakuyaku, Shao Yao, Tree Peony, Ud Saleeb, Udsalam, Udsalap, White Peony
Actions: Anti-allergenic, Anti-angiogenic, Anti-cancer, Anti-inflammatory, Anti-mutagenic, Antioxidant, Anti-proliferative, Anti-tumor, Antiviral, Apoptotic, Coronary heart disease preventive, Cytoprotective, Cytotoxic, DNA protective, Estrogenic, Gastric disorders (, &lt;em&gt;Campylobacter pyloridis&lt;/em&gt;, ) treatment, Hemolytic, Hormonal, Hypertension (gestational) treatment, Hypertonic, Immunologic, Inhibitory, Lipid-lowering, Menstrual/ovulation, Muscular, Neuroprotective, Progesterogenic, Uterine fibroid reduction, Vasodilatory
Background
Peony (Paeonia lactiflora) is an herb. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes.
Peony might block chemicals that can cause pain and swelling. It might also prevent blood clotting, kill cancer cells, and act as an antioxidant. Peony is sometimes called red peony and white peony. This refers to the color of the processed root, not the color of the flowers.
People use peony for menstrual cramps, aging skin, cough, epilepsy, psoriasis, and many other conditions, but there is no good scientific evidence to support these uses.
Peony might block chemicals that can cause pain and swelling. It might also prevent blood clotting, kill cancer cells, and act as an antioxidant. Peony is sometimes called red peony and white peony. This refers to the color of the processed root, not the color of the flowers.
People use peony for menstrual cramps, aging skin, cough, epilepsy, psoriasis, and many other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: Peony is possibly safe when used for up to 6 months. It can cause stomach upset in some people. There isn't enough reliable information to know if peony is safe to use long-term.
When applied to the skin: There isn't enough reliable information to know if peony is safe. It can cause rash in some people.
Breast-feeding: There isn't enough reliable information to know if peony is safe to use while breast-feeding. Stay on the safe side and avoid use.
Children: Peony is possibly safe when taken by mouth for up to 12 months by children at least 1 year old.
Bleeding disorders: Peony might slow blood clotting. Don't use it if you have a bleeding disorder.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Peony extract might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use peony.
Surgery: Peony might slow blood clotting. This might increase the chance of bleeding during and after surgery. Stop using peony at least 2 weeks before a scheduled surgery.
When applied to the skin: There isn't enough reliable information to know if peony is safe. It can cause rash in some people.
Special Precautions & Warnings:
Pregnancy: Peony is possibly unsafe when taken by mouth during pregnancy. It might cause uterine contractions. Until more is known, don't use peony during pregnancy.Breast-feeding: There isn't enough reliable information to know if peony is safe to use while breast-feeding. Stay on the safe side and avoid use.
Children: Peony is possibly safe when taken by mouth for up to 12 months by children at least 1 year old.
Bleeding disorders: Peony might slow blood clotting. Don't use it if you have a bleeding disorder.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Peony extract might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use peony.
Surgery: Peony might slow blood clotting. This might increase the chance of bleeding during and after surgery. Stop using peony at least 2 weeks before a scheduled surgery.
Effectiveness
Effective Effectiveness definitions
There is interest in using peony for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Birth control pills (Contraceptive drugs)
Interaction Rating=Moderate Be cautious with this combination.
Some birth control pills contain estrogen. Peony might have some of the same effects as estrogen. Taking peony along with birth control pills might increase the risk of side effects. It might also decrease the effects of birth control pills. If you take birth control pills along with peony, use an additional form of birth control such as a condom.
Clozapine (Clozaril)
Interaction Rating=Moderate Be cautious with this combination.
Peony might increase the amount of clozapine in the body. Taking peony along with clozapine might increase the effects and side effects from clozapine.
Estrogens
Interaction Rating=Moderate Be cautious with this combination.
Peony might have some of the same effects as estrogen. Taking peony along with estrogen might increase the effects and side effects from estrogen.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Peony might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Peony might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Moderate Be cautious with this combination.
Peony might slow blood clotting. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Phenytoin (Dilantin)
Interaction Rating=Moderate Be cautious with this combination.
Peony root might decrease the amount of phenytoin in the body. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures.
Interactions with herbs & supplements
Herbs and supplements that might slow blood clotting: Peony might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
Herbs that might act like estrogen: Peony might have the same effects as estrogen. Using it along with other supplements with similar effects might increase estrogen-like effects and side effects. Examples of supplements with this effect include black cohosh, hops, kudzu, and red clover.
Herbs that might act like estrogen: Peony might have the same effects as estrogen. Using it along with other supplements with similar effects might increase estrogen-like effects and side effects. Examples of supplements with this effect include black cohosh, hops, kudzu, and red clover.
Interactions with foods
There are no known interactions with foods.
Products
View all products
Per tablet:
Per tablet:
Per 1.2 g:
Per tablet:
- Paeonia lactiflora (Peony) ext. 71.43 mg
- Vitex agnus-castus ext. 50 mg
- Angelica polymorpha ext. 250 mg
- Brassica oleracea var. italica ext. 20 mg
- Viburnum opulus ext. 30 mg
- Asparagus racemosus ext. 50 mg
- Zingiber officinale ext. 22.75 mg
- Withania somnifera ext. 20 mg
- Curcuma longa ext. 10 mg
- Nicotinamide (Vitamin B3) 15 mg
- Pyridoxine hydrochloride (Vitamin B6) 10 mg equiv. pyridoxine 8.2 mg
- Magnesium citrate anhydrous 308.6 mg equiv. magnesium 47.7 mg
- Corydalis ambigua ext. 30 mg
Per capsule:
Per capsule:
Per tablet:
- Paeonia lactiflora (Peony) ext. 28.57 mg
- Angelica polymorpha ext. 50 mg
- Dioscorea oppositifolia ext. 40 mg
- Bupleurum falcatum ext. 20 mg
- Cholecalciferol 2.5 μg equiv. vitamin D3 100 IU
- Vitex agnus-castus ext. 10 mg
- Rehmannia glutinosa ext. 200 mg
- Calcium hydrogen phosphate 350 mg equiv. calcium 81.6 mg equiv. phosphorus 63 mg
- Calcium amino acid chelate 50 mg equiv. calcium 10 mg
- Magnesium amino acid chelate 50 mg equiv. magnesium 10 mg
Per tablet:
- Paeonia lactiflora (Peony) ext. 28.57 mg
- Angelica polymorpha ext. 50 mg
- Dioscorea oppositifolia ext. 40 mg
- Bupleurum falcatum ext. 20 mg
- Ziziphus jujuba ext. 200 mg
- Vitex agnus-castus ext. 10 mg
- Rehmannia glutinosa ext. 200 mg
- Calcium hydrogen phosphate dihydrate 350 mg equiv. calcium 81.6 mg equiv. phosphorus 63 mg
- Magnesium amino acid chelate 50 mg equiv. magnesium 10 mg
- Cholecalciferol 2.5 μg equiv. vitamin D3 100 IU
- Rehmannia glutinosa ext. 633.33 mg
- Calcium amino acid chelate 50 mg equiv. calcium 10 mg
Per capsule:
- Paeonia suffruticosa (Mu Dan Pi) ext. 22.68 mg
- Paeonia lactiflora (Bai Shao) ext. 22.71 mg
- Paeonia veitchii (Chi Shao) ext. 22.71 mg
- Salvia miltiorrhiza ext. 32.7 mg
- Scutellaria baicalensis ext. 32.7 mg
- Atractylodes macrocephala ext. 22.68 mg
- Bupleurum falcatum ext. 22.68 mg
- Lycium barbarum ext. 22.68 mg
- Glycyrrhiza uralensis ext. 10.08 mg
- Ziziphus jujuba ext. 25.2 mg
- Citrus aurantium ext. 22.68 mg
- Pseudostellaria heterophylla ext. 22.68 mg
- Curcuma longa ext. 22.68 mg
Per capsule:
- Paeonia suffruticosa (Mu Dan Pi) ext. 11.31 mg
- Paeonia lactiflora (Bai Shao) ext. 18.84 mg
- Paeonia veitchii (Chi Shao) ext. 18.84 mg
- Angelica polymorpha ext. 18.84 mg
- Daemonorops draco ext. 11.31 mg
- Drynaria fortunei ext. 11.31 mg
- Dipsacus asper ext. 11.31 mg
- Prunus persica ext. 11.31 mg
- Boswellia carterii ext. 11.31 mg
- Commiphora myrrha ext. 11.31 mg
- Sparganium stoloniferum ext. 11.31 mg
- Curcuma zedoaria ext. 11.31 mg
- Saposhnikovia divaricata ext. 11.31 mg
- Citrus aurantium ext. 11.31 mg
- Curcuma longa ext. 11.31 mg
- Platycodon grandiflorus ext. 11.31 mg
- Panax notoginseng ext. 7.53 mg
- Glycyrrhiza uralensis ext. 6.27 mg
- Carthamus tinctorius ext. 11.31 mg
- Corydalis turtschaninovii ext. 18.84 mg
- Cyathula officinalis ext. 15.06 mg
- Salvia miltiorrhiza ext. 18.84 mg
- Siphonestegia chinesis ext. 11.31 mg
Per capsule:
- Paeonia lactiflora (Bai Shao) ext. 37.47 mg
- Paeonia veitchii (Chi Shao) ext. 37.47 mg
- Rehmannia glutinosa ext. 74.94 mg
- Angelica polymorpha ext. 37.47 mg
- Cyperus rotundus ext. 28.23 mg
- Ligusticum striatum ext. 28.14 mg
- Prunus persica ext. 28.14 mg
- Carthamus tinctorius ext. 28.14 mg
Per capsule:
- Paeonia suffruticosa (Mu Dan Pi) ext. 26.87 mg
- Paeonia obovata (Chi Shao) ext. 26.87 mg
- Rehmannia glutinosa ext. 41.79 mg
- Poria cocos ext. 32.84 mg
- Phellodendron amurense ext. 26.87 mg
- Anemarrhena asphodeloides ext. 26.87 mg
- Alisma orientale ext. 26.87 mg
- Cornus officinalis ext. 23.88 mg
- Glycyrrhiza uralensis ext. 11.94 mg
- Lindera strychnifolia ext. 26.87 mg
- Cyathula officinalis ext. 26.87 mg
Per capsule:
- Paeonia lactiflora (Bai Shao) ext. 26.66 mg
- Paeonia obovata (Chi Shao) ext. 26.66 mg
- Rehmannia glutinosa ext. 39.97 mg
- Pseudostellaria heterophylla ext. 31.97 mg
- Salvia miltiorrhiza ext. 39.97 mg
- Dioscorea oppositifolia ext. 39.97 mg
- Astragalus membranaceus ext. 31.97 mg
- Ophiopogon japonicus ext. 26.66 mg
- Trichosanthes kirilowii ext. 26.66 mg
- Coptis chinensis ext. 8.03 mg
Per capsule:
- Paeonia lactiflora (Bai Shao) ext. 24.87 mg
- Paeonia veitchii (Chi Shao) ext. 24.87 mg
- Salvia miltiorrhiza ext. 24.89 mg
- Corydalis turtschaninovii ext. 24.89 mg
- Angelica polymorpha ext. 24.87 mg
- Typha angustifolia ext. 24.87 mg
- Prunus persica ext. 22.39 mg
- Ligusticum striatum ext. 22.39 mg
- Cyperus rotundus ext. 22.39 mg
- Lindera strychnifolia ext. 22.39 mg
- Curcuma zedoaria ext. 22.39 mg
- Panax notoginseng ext. 14.93 mg
Per capsule:
- Paeonia lactiflora (Peony) ext. 21.6 mg
- Paeonia obovata (Chi Shao) ext. 21.6 mg
- Rehmannia glutinosa ext. 36 mg
- Salvia miltiorrhiza ext. 36 mg
- Achyranthes bidentata ext. 28.8 mg
- Prunus persica ext. 21.6 mg
- Carthamus tinctorius ext. 21.6 mg
- Ligusticum striatum ext. 21.6 mg
- Bupleurum falcatum ext. 21.6 mg
- Citrus aurantium ext. 21.6 mg
- Platycodon grandiflorus ext. 14.4 mg
- Glycyrrhiza uralensis ext. 12 mg
- Angelica polymorpha ext. 21.6 mg
Per capsule:
- Paeonia lactiflora (Bai Shao) ext. 19.05 mg
- Paeonia obovata (Chi Shao) ext. 19.05 mg
- Curcuma longa ext. 19.05 mg
- Bupleurum falcatum ext. 14.28 mg
- Salvia miltiorrhiza ext. 23.82 mg
- Artemisia frigida ext. 23.82 mg
- Poria cocos ext. 23.82 mg
- Morindae officinalis ext. 23.82 mg
- Scutellaria baicalensis ext. 19.05 mg
- Codonopsis pilosula ext. 19.05 mg
- Atractylodes macrocephala ext. 19.05 mg
- Pinellia ternata ext. 14.28 mg
- Lycium barbarum ext. 14.28 mg
- Glehnia littoralis ext. 14.28 mg
- Polygonatum officinale ext. 14.28 mg
- Citrus reticulata ext. 9.51 mg
- Glycyrrhiza uralensis ext. 9.51 mg
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This monograph was last reviewed on 23/11/2022 01:01:39 and last updated on 15/10/2020 02:46:06. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
