• May provide mood support
  • May help to support normal healthy liver function

Dosage & warnings

1 - 3 tablets daily

Contains vitamin B6
Stop taking this medication if you experience tingling, burning or numbness and see your healthcare practitioner as soon as possible
Individuals who are using prescription antidepressants, monoamine oxidase inhibitors or suffer from bipolar depression should not use this product unless under the supervision of a healthcare practitioner
Use of SAMe in pregnancy should only be considered when benefits clearly outweigh the potential risks
There is insufficient reliable information available about the use of SAMe at higher doses, for extended periods of time, or during the earlier trimesters of pregnancy
Not advised during lactation due to insufficient safety data

Only take as directed.


Adonat® S-Adenosylmethionine disulfate tosylate (SAMe)
equiv. S-Adenosylmethionine
400 mg
200 mg
Pyridoxine hydrochloride (Vitamin B6)
equiv. Pyridoxine
25 mg
20.6 mg
Zinc amino acid chelate
equiv. Zinc
25 mg
5 mg
Riboflavin (Vitamin B2) 10 mg
Pyridoxal 5-phosphate (P5P)
equiv. Pyridoxine
5 mg
3.5 mg


This product is listed with the TGA - AustL 324082. The TGA publishes product info, including excipients under the "Other ingredients" subheading (not typically listed on the product label). Download the TGA public summary below.