Yellow lupin
Yellow lupin

People use this for...

Orally, yellow lupin is used for urinary tract disorders, as an anthelmintic for worm infestations, and as a diuretic.
Topically, yellow lupin is used for ulcers.

Possibly Unsafe ...when the seeds or above ground parts are used orally (18). There is insufficient reliable information available about the topical safety of yellow lupin.

Possibly Unsafe ...when used orally (18); avoid using.

There is insufficient reliable information available about the effectiveness of yellow lupin.

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Dosing & administration

    Adverse effects

    General: Orally, the symptoms of poisoning following ingestion include salivation, vomiting, dysphagia, cardiac arrhythmias, ascending paralysis and possibly death due to respiratory failure (18).

    Interactions with pharmaceuticals

    None known.

    Interactions with herbs & supplements

    None known.

    Interactions with foods

    None known.

    Interactions with lab tests

    None known.

    Interactions with diseases

    None known.

    Mechanism of action

    Yellow lupin contains 0.6-1.6% quinolizidine alkaloids in the above ground plant parts, including sparteine, 13-hydroxylupanine, lupinines and p-cumaroyllupinine. The seed contain 0.4-3.3% quinolizidine alkaloids, including lupinines, sparteine, and in some cultivated strains, gramine. At present, we don't know how these components relate to the uses of lupin. Poisoning has been seen in animals, and is known as "lupinosis". It is due to the presence of mycotoxins that are produced by the fugus Phomopsis leptostromiformis, which sometimes lives in lupins (18).


    18Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998. has licensed professional monographs from TRC Healthcare. Full monographs are available to Pro practitioner accounts.
    This monograph was last reviewed on 18/09/2020 20:17:37 and last updated on 21/12/2012 19:57:13. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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