Nadh
Nadh

Background

NADH stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H)." It occurs naturally in the body and plays a role in generating energy.

The NADH produced by the body is involved in making energy in the body. Taking NADH supplements might affect blood pressure and have other effects.

People use NADH for chronic fatigue syndrome (CFS), high blood pressure, high cholesterol, athletic performance, depression, Parkinson disease, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse NADH with niacin, niacinamide, or nicotinamide riboside. These are not the same.
When taken by mouth: NADH is possibly safe for most people when used for up to 12 weeks. It's usually well-tolerated.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if NADH is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Chronic fatigue syndrome (CFS). Taking NADH by mouth, alone or together with coenzyme Q10, might somewhat reduce symptoms of CFS.
There is interest in using NADH for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

NADH has most often been used by adults in doses of 5-10 mg by mouth daily for up to 24 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

It is not known if NADH interacts with any medicines. Before taking NADH, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 26/08/2023 10:00:00 and last updated on 09/09/2022 06:17:06. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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