Histidine
Scientific names: Histidine
Alternative names: (2S)-2-Amino-3-(1H-Imidazol-5-yl) Propanoic Acid, (S)-4-(2-Amino-2-Carboxyethyl) Imidazole, Histidina, L-Histidine, L-Histidine AKG, L-Histidine-Alpha Ketoglutaric Acid, L-Histidine HCl, Levo-Histidine, (S)-Alpha-Amino-1H-imidazole-4-Propanoic Acid
Background
Histidine is an essential amino acid. It is not made by the body, but is consumed in foods. Amino acids are the building blocks of protein.
Histidine is involved in many different metabolic processes in the body.
People use histidine for diarrhea due to cholera infection, eczema, kidney failure, metabolic syndrome, and many other conditions, but there is no good scientific evidence to support these uses.
Histidine is involved in many different metabolic processes in the body.
People use histidine for diarrhea due to cholera infection, eczema, kidney failure, metabolic syndrome, and many other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: Histidine is commonly consumed as part of the diet. Histidine supplements are possibly safe when used short-term. Doses of up to 4 grams daily have been used safely for up to 12 weeks. It seems to be well-tolerated.
Folic acid deficiency: People with folic acid deficiency should avoid histidine. It can cause an unwanted chemical called formiminoglutamic acid (FIGLU) to build up in the body.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Histidine is commonly consumed as part of the diet. There isn't enough reliable information to know if histidine is safe to use in larger amounts as medicine when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.Folic acid deficiency: People with folic acid deficiency should avoid histidine. It can cause an unwanted chemical called formiminoglutamic acid (FIGLU) to build up in the body.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- An infection of the intestines that causes diarrhea (cholera). Drinking a solution containing histidine seems to reduce diarrhea in people with cholera who are also receiving antibiotics.
Dosing & administration
Histidine is a natural part of the diet. L-histidine supplements have most often been used by adults in doses of 4 grams by mouth daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
It is not known if Histidine interacts with any medicines. Before taking Histidine, talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
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Per 30 g (Vanilla Bean):
1 kg Vanilla Bean
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1 kg Natural
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Per 30 g (Creamy Vanilla):
- Pea protein isolate
- Medium chain triglycerides (MCT)
- Natural flavours
- Linum usitatissimum (seed) (Flaxseed)
- Plantago ovata (husk) (Psyllium)
- Sunflower seed
- Quinoa powder
- Amaranth powder
- Vaccinium corymbosum powder
- Rubus idaeus powder
- Euterpe oleracea (berry) ext. (Acai)
- L-leucine
- L-isoleucine
- L-valine
- L-glutamine
- Levocarnitine (L-carnitine)
- Stevia rebaubiana
- Fagopyrum esculentum powder
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Per 30 g (Vanilla Bean):
- Whey protein isolate 29.94 g
- Sunflower lecithin
- Natural flavours
- Stevia rebaubiana
- Vanilla planifolia (Vanilla bean)
- Bacillus coagulans (MTCC 5260)
- Protease
- Amylase enzyme
- Cellulase
- Lactase
- Lipase
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Per 35 g (Chocolate):
- Cannabis sativa powder 20.65 g
- Coconut milk powder
- Vanilla planifolia (Vanilla bean extract)
- Sunflower lecithin
- Silica - colloidal anhydrous
- Thaumatin
- Theobroma cacao powder 9.8 g
- Natural chocolate flavour
- Natural flavours
- Tapioca maltodextrin
- Acacia sp.
420 g Chocolate
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Per 36.8 g (Vanilla):
- Pea protein concentrate
- Oryza sativa (Rice protein)
- Hordeum vulgare
- Wheatgrass powder
- Amaranth powder
- Quinoa powder
- Medicago sativa
- Malus (Apple)
- Vaccinium corymbosum
- Vaccinium macrocarpon
- Daucus carota powder (Carrot)
- Coriandrum sativum
- Petroselinum crispum
- Cynara scolymus
- Raphanus raphanistrum (Wild radish)
- Taraxacum officinale
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Apium graveolens
- Beta vulgaris
- Spinacia oleracea (Spinach)
- Lycopersicon esculentum (Tomato)
- Brassica oleracea var. italica
- Armoracia rusticana
- Brassica oleracea var. viridis
- Nasturtium officinale
- Ocimum basilicum
- Piper nigrum
- Mentha spicata
- Natural flavours
- Malpighia glabra ext. dry
- Cordyceps sinensis
- Ganoderma lucidum
- Lentinula edodes
- Grifola frondosa
- Trametes versicolor
- Cannabis sativa (seed) powder
- Agaricus subrufescens
- Stevia rebaubiana
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Per 7 g (Lemonade):
- L-histidine
- Schisandra chinensis ext. equiv. dry 2.5 g
- L-leucine
- L-isoleucine
- L-methionine
- L-threonine
- L-valine
- L-lysine
- L-phenylalanine
- L-tryptophan
- Calcium citrate
- Magnesium bisglycinate
- Flavour
- Silica - colloidal anhydrous
- Ascorbic acid (Vitamin C)
- Potassium citrate
- Pyridoxal 5-phosphate (P5P)
- Methylcobalamin (Activated B12)
- Stevia rebaubiana
420 g Lemonade
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400 g Natural
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Per 30 g (Vanilla):
- Golden pea protein (sprout) bio-fermented
- Oryza sativa (Brown rice protein fermented)
- Pea (fibre) sprouted
- Ananas comosus (Bromelain)
- Stevia rebaubiana (leaf)
- Acacia sp. (gum)
1 kg Vanilla
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Per 30 g (Triple Chocolate):
- Golden pea protein (sprout) bio-fermented
- Natural flavours
- Sea mineral complex
- Spinacia oleracea (Spinach)
- Arthrospira platensis (Spirulina)
- Chlorella pyrenoidosa powder
- Cinnamomum verum powder
- Glycyrrhiza glabra powder
- Zingiber officinale powder
- Taraxacum officinale powder
- Ginkgo biloba powder
- Eleutherococcus senticosus powder
- Silybum marianum powder
- Capsicum spp. powder
- Centella asiatica powder
- Syzygium aromaticum powder
- Stevia rebaubiana (leaf) ext.
- Ananas comosus (Bromelain)
- Theobroma cacao (Cocoa powder)
- Acacia sp. (gum)
1 kg Triple Chocolate
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Per 30 g serve (Natural Chocolate):
- Organic Pea Protein
- Vicia faba (Fava bean protein)
- Coconut medium-chain triglyceride (Coconut MCT)
- Rice Peptides
- Organic Coconut Milk Powder
- Natural vanilla flavour
- Natural caramel flavour
- Cyamopsis tetragonoloba (Guar gum)
- Stevia rebaubiana
- Luo Han Guo (fruit) ext. (Monk fruit)
- Organic Alkalised Cocoa Powder
- Natural chocolate flavour
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Per 30 g (Chocolate):
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Per 37.5 g:
- Histidine hydrochloride 185.25 mg equiv. l-histidine 150 mg
- L-leucine 1.68 g
- Lysine hydrochloride 451.03 mg equiv. l-lysine 361 mg
- L-isoleucine 450 mg
- L-valine 450 mg
- L-phenylalanine 200 mg
- Cysteine hydrochloride 45 mg equiv. l-cystine 31.04 mg
- L-methionine 120 mg
- L-tyrosine 112.5 mg
- L-aspartic acid 111 mg
- L-proline 111 mg
- L-serine 27.75 mg
- L-alanine 27.75 mg
- L-glycine 27.75 mg
- Taurine 11 mg
- Levocarnitine tartrate (L-carnitine) 10.99 mg equiv. levocarnitine 7.5 mg
- Zinc sulphate monohydrate 5.66 mg equiv. zinc 2.08 mg
- Sodium ascorbate (Vitamin C) 22.5 mg equiv. ascorbic acid 20 mg
- d-alpha-Tocopheryl acetate 10 mg equiv. vitamin E 10 IU
- Retinol palmitate 421.72 ÎĽg equiv. vitamin A 767 IU
- Cholecalciferol 1.65 ÎĽg equiv. vitamin D3 66 IU
- Cyanocobalamin (Vitamin B12) 2 ÎĽg
- L-glutamine 2.22 g
- L-threonine 200 mg
- Ferrous fumarate 4.6 mg equiv. iron 1.5 mg
- Manganese sulphate monohydrate 1.04 mg equiv. manganese 330 ÎĽg
- Selenomethionine 37.5 ÎĽg equiv. selenium 11.54 ÎĽg
- Copper sulfate pentahydrate 675 ÎĽg equiv. copper 167 ÎĽg
- Molybdenum trioxide 11.25 ÎĽg equiv. molybdenum 8 ÎĽg
- Chromium picolinate 30.87 ÎĽg equiv. chromium 3.84 ÎĽg
- Potassium iodide 225 ÎĽg equiv. iodine 17 ÎĽg
- Borax 2.25 mg equiv. boron 250 ÎĽg
- Choline bitartrate 80.84 mg equiv. choline 33.25 mg
- Nicotinamide (Vitamin B3) 3.25 mg
- Pyridoxine hydrochloride (Vitamin B6) 790 ÎĽg equiv. pyridoxine 650 ÎĽg
- Riboflavin (Vitamin B2) 500 ÎĽg
- Thiamine nitrate (Vitamin B1) 616.83 ÎĽg equiv. thiamine 500 ÎĽg
- Biotin 50 ÎĽg
- Calcium pantothenate (Vitamin B5) 3.53 mg equiv. pantothenic acid 3.25 mg
- Phytomenadione (Vitamin K1) 10 ÎĽg
- Glucose monohydrate (Dextrose) 12.5 g
- Sunflower lecithin 250 mg
- Potassium citrate 403 mg equiv. potassium 145.75 mg
- Folic acid 31.27 ÎĽg
- Calcium glycerophosphate 392.66 mg equiv. calcium 75 mg
- Calcium phosphate 62.7 mg equiv. calcium 25 mg
- Magnesium glycerophosphate 50.1 mg equiv. magnesium 6.25 mg
- Magnesium citrate 166.65 mg equiv. magnesium 27 mg
- Chromic chloride hexahydrate 46.95 ÎĽg equiv. chromium 9.16 ÎĽg
- Levomefolate glucosamine (Activated folate) 8 ÎĽg equiv. levomefolic acid 4.5 ÎĽg
- Medium Chain Triglycerides (powder) (MCT) 3 g
Practitioner product
Per 35.2 g:
- Histidine hydrochloride 185.25 mg equiv. l-histidine 150 mg
- L-glutamine 2.22 g
- L-leucine 1.68 g
- Lysine hydrochloride 451.03 mg equiv. l-lysine 361 mg
- L-isoleucine 450 mg
- L-valine 450 mg
- L-phenylalanine 200 mg
- L-threonine 200 mg
- Cysteine hydrochloride 45 mg equiv. cysteine 31.04 mg
- L-methionine 120 mg
- L-tyrosine 112.5 mg
- L-aspartic acid 111 mg
- L-proline 111 mg
- L-serine 27.75 mg
- L-alanine 27.75 mg
- Glycine 27.75 mg
- Taurine 11 mg
- Zinc sulphate monohydrate 5.7 mg equiv. zinc 2.08 mg
- Sodium ascorbate (Vitamin C) 22.5 mg equiv. ascorbic acid 20 mg
- d-alpha-Tocopheryl acetate 10 mg equiv. vitamin E 10 IU
- Retinol palmitate (Vitamin A) 421.72 µg equiv. vitamin A 230.21 µg equiv. vitamin A 767 IU
- Cyanocobalamin (Vitamin B12) 2 µg
- Levocarnitine tartrate (L-carnitine) 10.99 mg equiv. levocarnitine 7.5 mg
- Potassium citrate 402.65 mg equiv. potassium 145.75 mg
- Magnesium citrate 166.67 mg equiv. magnesium 27 mg
- Ferrous fumarate 4.6 mg equiv. iron 1.5 mg
- Manganese sulphate monohydrate 10.14 mg equiv. manganese 330 µg
- Selenomethionine 28.59 µg equiv. selenium 11.54 µg
- Copper sulfate pentahydrate 654.7 µg equiv. copper 167 µg
- Molybdenum trioxide 10.56 µg equiv. molybdenum 8 µg
- Chromium picolinate 30.87 ÎĽg equiv. chromium 3.84 ÎĽg
- Potassium iodide 22 µg equiv. iodine 17 µg
- Borax 2.20 mg equiv. boron 250 µg
- Choline bitartrate 80.89 mg equiv. choline 33.25 mg
- Nicotinamide (Vitamin B3) 3.25 mg
- Pyridoxine hydrochloride (Vitamin B6) 790 µg equiv. pyridoxine 650 µg
- Cholecalciferol 1.65 µg equiv. vitamin D3 66 IU
- Riboflavin (Vitamin B2) 500 µg
- Thiamine nitrate (Vitamin B1) 616.83 µg equiv. thiamine 500 µg
- Folic acid 31.27 µg
- Biotin 50 µg
- Calcium pantothenate (Vitamin B5) 3.53 mg equiv. pantothenic acid 3.25 mg
- Phytomenadione (Vitamin K1) 10 µg
- Glucose monohydrate 12.5 g
- Sunflower lecithin 250 mg
- Magnesium glycerophosphate 50.12 mg equiv. magnesium 6.25 mg
- Calcium glycerophosphate 392.73 mg equiv. calcium 75 mg
- Calcium phosphate 62.62 mg equiv. calcium 25 mg
- Chromic chloride hexahydrate 46.95 ÎĽg equiv. chromium 9.16 ÎĽg
- Levomefolate glucosamine (Activated folate) 8 ÎĽg equiv. levomefolic acid 4.5 ÎĽg
- Medium Chain Triglycerides (powder) (MCT) 3 g
Practitioner product
Per capsule:
Practitioner product
Per 30 g (Passionfruit):
- L-histidine
- Hydrolysed pea protein
- L-alanine
- Glycine
- L-valine
- L-leucine
- L-isoleucine
- L-proline
- L-phenylalanine
- L-tyrosine
- L-serine
- L-threonine
- L-methionine
- L-arginine
- L-lysine
- L-aspartic acid
- L-glutamic acid
- L-tryptophan
- L-cysteine
- Natural flavours
- Cichorium intybus (root) (Chicory)
- Acacia sp. (gum)
- Coconut water powder
- Medium chain triglycerides (MCT)
- Potassium citrate
- Magnesium citrate
- Sodium chloride (Salt)
- Calcium citrate
- Ascorbic acid (Vitamin C)
- Citric acid anhydrous
- Stevia rebaubiana
- Thaumatin
- Beta-carotene
- Riboflavin (Vitamin B2)
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
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