Glycine
Scientific names: Aminoacetic Acid
Alternate names: Acide Aminoacétique, Acide Amino-Acétique, Athenon, Free Base Glycine, G Salt, Glicina, Glycine de Base Libre, Glycocoll, Glycosthene, Iconyl, L-Glycine, Monazol
Actions: Anti-cancer, Antioxidant, Central nervous system (CNS), Cyclosporine-protective, Hepatoprotective, Sleep
Background
Glycine is an amino acid. The body can make glycine on its own, but it is also consumed in the diet. Sources include meat, fish, dairy, and legumes.
Glycine is a building block for making proteins in the body. Glycine is also involved in transmitting chemical signals in the brain, so there's interest in using it for schizophrenia and improving memory. A typical diet contains about 2 grams of glycine daily.
People use glycine for schizophrenia, stroke, memory and thinking skills, insomnia, and many other purposes, but there is no good scientific evidence to support most of these uses.
Glycine is a building block for making proteins in the body. Glycine is also involved in transmitting chemical signals in the brain, so there's interest in using it for schizophrenia and improving memory. A typical diet contains about 2 grams of glycine daily.
People use glycine for schizophrenia, stroke, memory and thinking skills, insomnia, and many other purposes, but there is no good scientific evidence to support most of these uses.
Safety Safety definitions
When taken by mouth: Glycine is possibly safe for most people when taken in doses up to 6 grams daily for 4 weeks. It's usually well-tolerated. Some people might have mild side effects such as stomach upset.
When applied to the skin: There isn't enough reliable information to know if glycine is safe or what the side effects might be.
When applied to the skin: There isn't enough reliable information to know if glycine is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if glycine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Schizophrenia. Taking glycine by mouth along with some antipsychotic drugs seems to reduce certain symptoms, called negative symptoms, in some people who don't respond to treatment with conventional drugs. But it's not clear if glycine is helpful in people who are taking newer medications, such as clozapine.
Dosing & administration
Glycine has most often been used by adults in doses of 3 grams by mouth daily for up to 24 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Clozapine (Clozaril)
Interaction Rating=Moderate Be cautious with this combination.
Clozapine is used to help treat schizophrenia. Taking glycine along with clozapine might decrease the effects of clozapine. It is not clear why this interaction occurs. Do not take glycine if you are taking clozapine.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
View all products
Per 5 g (Lemon Lime):
RRP: $76.67$65.18Save: 15%
RRP: $49.95$37.47Save: 25%
RRP: $79.95$54.36Save: 32%
Per 6 g:
- L-glycine 500 mg
- Hydrolysed marine collagen 3 g
- Ascorbic acid (Vitamin C) 200 mg
- Silica - colloidal anhydrous 320.85 mg equiv. silica 150 mg
- Haematococcus pluvialis ext. 80 mg
- Aloe barbadensis ext. 50 mg
- Curcuma longa ext. 80 mg
- Eleutherococcus senticosus ext. 33.36 mg
- Quercetin dihydrate 100 mg
- d-alpha-Tocopheryl acid succinate 41.34 mg equiv. vitamin E 67.5 IU
- L-glutamine 750 mg
- Vaccinium myrtillus juice dry 100 mg
RRP: $69.99$58.80Save: 16%
Per 5 g (Lemon Lime):
RRP: $55.70$47.34Save: 15%
Per tablet:
- Glycine 50 mg
- Silybum marianum ext. 60 mg
- Foeniculum vulgare ext. 150 mg
- Taraxacum officinale ext. 25 mg
- Brassica oleracea var. italica ext. 35 mg
- Glutamine 100 mg
- Curcuma longa ext. 80 mg
- Schisandra chinensis ext. 20 mg
- Sodium molybdate dihydrate 126 µg equiv. molybdenum 50 µg
- Taurine 150 mg
- Choline bitartrate 100 mg equiv. choline 41 mg
- Inositol 100 mg
RRP: $44.99$37.80Save: 16%
RRP: $70.50$49.35Save: 30%
Per tablet:
RRP: $53.96$37.77Save: 30%
Out of stock with supplier
Restock unknown
Per tablet:
- Glycine 10 mg
- Glucosamine hydrochloride 1.5 g equiv. glucosamine 1.245 g
- Sodium chondroitin sulphate (bovine) 130 mg equiv. chondroitin sulphate 120 mg
- Dimethyl sulfone (MSM) 100 mg
- L-proline 10 mg
- Silica - colloidal anhydrous 10 mg equiv. silicon 4.67 mg
- Zinc oxide 6.23 mg equiv. zinc 5 mg
- Manganese sulphate monohydrate 9.23 mg equiv. manganese 3 mg
- Zingiber officinale ext. 50 mg
RRP: $45.00$31.50Save: 30%
Per 10 g (Berry):
- L-glycine
- Schisandra chinensis
- Berberis vulgaris
- Cynara scolymus
- Silybum marianum
- Passionfruit
- Citrus limon (Lemon)
- Piper nigrum
- Zingiber officinale
- Camellia sinensis
- Beta vulgaris
- Ribes nigrum
- L-glutamine
- L-methionine
- Zinc gluconate
- Taurine
- Choline bitartrate
- Pyridoxine hydrochloride (Vitamin B6)
- Folic acid
- Selenomethionine (Selenium)
- Cyanocobalamin (Vitamin B12)
- Apple pectin
- Riboflavin (Vitamin B2)
- Natural flavours
- Rosmarinus officinalis
- Echinacea angustifolia
- Malpighia glabra
- Curcuma longa
- L-cysteine
- Oryza sativa (Rice hulls)
- Silicon dioxide
- Punica granatum
- Vaccinium corymbosum (fruit) powder
RRP: $59.95$46.76Save: 22%
300 g Chocolate
RRP: $99.95$89.96Save: 10%
Per 12.5 g (Mango Pineapple):
- Glycine
- Hydrolysed bovine collagen peptides
- Hydrolysed marine collagen
- L-glutamine
- Ascorbic acid (Vitamin C)
- L-tryptophan
- MCT powder
- Flavour
- Amylase enzyme
- Protease
- Lactase
- Lipase
- Cellulase
- Stevia rebaubiana
- Acacia sp. (fibre)
938 g Mango Pineapple
RRP: $89.95$80.96Save: 10%
Per 7 g (Berry):
- Glycine
- L-proline
- Silica - colloidal anhydrous
- Hyaluronic acid
- L-lysine
- Maltodextrin
- Vaccinium corymbosum
- Beta vulgaris
- Rosa canina
- Malpighia glabra
- Punica granatum
- Hibiscus sabdariffa
- Natural flavours
- Bambusa arundinacea ext.
- Luo Han Guo (fruit) ext. (Monk fruit)
- Aloe barbadensis ext.
- Zinc gluconate
RRP: $64.96$55.21Save: 15%
Discontinued by Wonder Foods
Per 5 g (Tropical Fruit):
- Glycine
- Magnesium citrate
- Magnesium oxide
- Potassium bicarbonate
- Potassium citrate
- Cholecalciferol (Vitamin D3)
- Malic acid
- L-glutamine
- Natural flavours
- Ananas comosus (Pineapple)
- Calcified lithothamnion (Red algae)
- Thiamine (Vitamin B1)
- Riboflavin (Vitamin B2)
- Niacinamide (Vitamin B3)
- Calcium pantothenate (Vitamin B5)
- Pyridoxine hydrochloride (Vitamin B6)
- Cyanocobalamin (Vitamin B12)
- Biotin
- Choline bitartrate
- Molybdenum
- L-Carnitine
- Calcium ascorbate (Vitamin C)
- Taurine
- Xanthan gum
- Luo Han Guo (fruit) ext. (Monk fruit)
- Citric acid anhydrous
- Tocopherols concentrate - mixed (Vitamin E)
- Selenium amino acid chelate
- Chromium nicotinate
RRP: $29.95$25.47Save: 15%
Discontinued by Wonder Foods
Per 6.5 g (Tropical Mint):
- Glycine
- Brassica oleracea (Broccoli)
- Spinacia oleracea (leaf)
- Brassica oleracea (leaf) powder (Kale)
- Hordeum vulgare
- Wheatgrass powder
- Hydrolysed marine collagen 0.81 g
- Natural coconut flavour
- Passionfruit
- Mentha x piperita oil
- Citric acid anhydrous
- Silica - colloidal anhydrous
- Ananas comosus (Pineapple)
- Mango (fruit)
- Daucus carota
- Xanthan gum
- Mango (fruit)
- Stevia rebaubiana
- Inulin (Dietary fibre)
RRP: $64.99$54.59Save: 16%
Per 35 g (Chocolate Fudge):
- L-glycine
- Oryza sativa (Brown rice)
- Vicia faba (Fava bean protein)
- Pumpkin seed protein
- Cannabis sativa (seed)
- L-glutamine
- L-valine
- L-threonine
- L-leucine
- L-arginine
- L-isoleucine
- Cocoa powder 3.24 g
- Natural flavours
- Malus powder (Apple)
- Acacia sp. (fibre)
- Siraitia grosvenorii (Monk fruit)
- Medium Chain Triglycerides
- Xanthan gum
- Eleutherococcus senticosus
- Coffea canephora
- Camellia sinensis
- Magnesium citrate
- Zinc gluconate
- Ferrous fumarate (Iron)
- Pink Himalayan crystal salt
- Laminaria digitara (Kelp)
- Ananas comosus (Bromelain)
- Carica papaya (Papain)
- Vitamin D
- Cyanocobalamin (Vitamin B12)
RRP: $44.95$35.06Save: 22%
Per 10 g:
- Glycine
- Asparagus racemosus
- Lepidium meyenii (root)
- Angelica polymorpha
- Paeonia lactiflora (root)
- Vitex agnus-castus
- Golden pea protein (sprout) bio-fermented
- Cannabis sativa
- Oryza sativa (sprout) (Brown rice)
- Eleutherococcus senticosus
- Camellia sinensis
- Berry flavour
- Beta vulgaris
- L-arginine hydrochloride
- Magnesium citrate
- Natural vanilla flavour
- Arthrospira platensis (Spirulina)
- Hordeum vulgare
- Lycium chinese (berry)
- Daucus carota
- Chickpea (sprout)
- Red lentil (sprout)
- Glycine max
- Sweet potato powder
- Avena sativa
- Oryza sativa (Rice)
- Linseed
- Pumpkin seed protein
- Sunflower seed
- Medicago sativa
- Laminaria digitara (Kelp)
- Wheat flour
- Molasses (Cane juice)
- Isomalt
- Zingiber officinale
- L-glutamine
- L-Carnitine
- Stevia rebaubiana (leaf)
- Siraitia grosvenorii (Monk fruit)
- Zinc gluconate
- Vigna angularis (Adzuki bean)
- Phaseolus vulgaris (Kidney bean)
RRP: $54.95$46.71Save: 15%
Per 30 g (Choc-Mint):
1 kg Choc-Mint
RRP: $69.95$57.71Save: 17%
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This monograph was last reviewed on 30/04/2023 10:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
