Croton seeds
Croton seeds


Croton is a plant. The seeds and oil extracted from the seeds are used to make medicine.

Despite serious safety concerns, people take croton seeds for constipation and other uses. Croton seeds are sometimes applied directly to the skin for rheumatoid arthritis (RA), gout, and other conditions.
When taken by mouth: Croton seeds and oil are UNSAFE when taken by mouth. A few drops of croton seed oil can cause death. Croton seeds and oil can cause burning of the mouth, vomiting, dizziness, painful bowel movements, and collapse.

When applied to the skin: Croton seeds and oil are UNSAFE when applied to the skin. If croton seed oil is put on the skin, it can cause itching, burning, and blistering.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Croton seeds are UNSAFE for anyone to use, but women who are pregnant should use extra care to avoid croton seeds because they can cause an abortion. Croton seeds are also UNSAFE to use if you are breast-feeding.


NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions
  • Blockage in the bowel.
  • Constipation.
  • Gallbladder disease.
  • Gout.
  • Malaria.
  • Nerve pain.
  • Rheumatoid arthritis (RA).
  • Swelling (inflammation) of the main airways in the lung (bronchitis).
  • Other conditions.
More evidence is needed to rate the effectiveness of croton seeds for these uses.

Dosing & administration

The appropriate dose of croton seeds depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for croton seeds. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Interactions with pharmaceuticals

It is not known if Croton Seeds interacts with any medicines. Before taking Croton Seeds, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.


Croton seeds and the oil from the seeds contain chemicals that have a powerful irritating effect on the stomach and intestines.
Discontinued by BioResearch
Practitioner product

BioMedica Virex Spray is a practitioner product.

Find a practitioner

Per serve:
Practitioner product

BioResearch Formula H is a practitioner product.

Find a practitioner

Practitioner product has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 18/09/2023 10:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. No reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. It is unlawful to download, store, or distribute content from this site.