People use this for...
Topically, corn cockle seeds are used for treating cancers, hard tumors, warts, hard swelling of the uterus, and to induce inflammation of the conjunctiva and cornea. The root is used for exanthemata (acute skin eruptions signifying a viral or coccal infection), and hemorrhoids.
Effectiveness Effectiveness definitions
There is insufficient reliable information available about the effectiveness of corn cockle.
Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Dosing & administration
General: Orally, corn cockle can cause GI irritation, severe muscle pain and twitching, depression, and coma (6). Acute poisoning symptoms include: diarrhea, salivation, vertigo, vomiting, paralysis, and respiratory depression (6). Repeated poisoning by small doses is referred to as "githagism" (6).
Interactions with pharmaceuticals
Interactions with herbs & supplements
Interactions with foods
Interactions with lab tests
Interactions with diseases
Mechanism of action
The applicable parts of corn cockle are the root and seed. Poisonous constituents, githagin and agrostemmic acid, are reportedly absorbed from the GI tract causing GI irritation, severe muscle pain and twitching, depression, and coma (6).
|6||The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.|