Chitosan
Scientific names: Chitosan
Alternate names: Ascorbate de Chitosane, Chitosan Ascorbate, Chitosane, Chitosane Déacétylé, Chitosane Mono-Carboxyméthylé, Chitosan-N-Acetylcysteine, Deacetylated Chitin, Deacetylated Chitosan, Enzymatic Polychitosamine Hydrolisat, HEP-30, Hydrolisat Enzymatique de Polychitosamine, Mono-Carboxymethylated Chitosan, N-Carboxybutyl Chitosan, N-Carboxybutyl Chitosane, O-Sulfated N-Acetylchitosan, Poly-D-Glucosamine, Poly-N-Acetyl-Glucosamine, Quitosano, Sulfated N-Carboxymethylchitosan, Sulfated O-Carboxymethylchitosan, Trimethyl Chitosan Chloride
Actions: Antibacterial activity, Antifungal, Antioxidant, Antitumor, Gastrointestinal, Hematologic, Lipid-lowering, Periodontal, Renal, Weight loss, Wound healing
Background
Chitosan is a sugar that comes from the outer skeleton of shellfish, including crab, lobster, and shrimp. It's used as medicine and in drug manufacturing.
Chitosan is a fibrous substance that might reduce how much fat and cholesterol the body absorbs from foods. It also helps blood clot when applied to wounds.
People use chitosan for high blood pressure, high cholesterol, obesity, wound healing, and many other purposes, but there is no good scientific evidence to support many of these uses.
Chitosan is a fibrous substance that might reduce how much fat and cholesterol the body absorbs from foods. It also helps blood clot when applied to wounds.
People use chitosan for high blood pressure, high cholesterol, obesity, wound healing, and many other purposes, but there is no good scientific evidence to support many of these uses.
Safety Safety definitions
When taken by mouth: Chitosan is possibly safe when used for up to 3 months. It might cause stomach upset, constipation, or gas.
When applied to the skin: Chitosan is possibly safe when used short-term.
Shellfish allergy: Chitosan is taken from the outer skeleton of shellfish. People with allergies to shellfish might also be allergic to chitosan.
When applied to the skin: Chitosan is possibly safe when used short-term.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if chitosan is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Shellfish allergy: Chitosan is taken from the outer skeleton of shellfish. People with allergies to shellfish might also be allergic to chitosan.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- High blood pressure. Replacing table salt with a table salt product that contains small amounts of chitosan (Symbiosal) might help lower blood pressure in people with high blood pressure.
- Obesity. Taking chitosan by mouth while on a calorie-restricted diet can improve weight loss in people who are overweight or obese, but only by a very small amount.
- Recovery after surgery. Applying a chitosan gel might help prevent scar tissue from forming in the sinuses after surgery.
Dosing & administration
Chitosan has most often been used by adults in doses of 1-1.35 grams by mouth daily for up to 12 weeks. It's also used in mouthwashes, gels, chewing gum, eye drops, and wound dressings. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.
Interactions with pharmaceuticals
Acyclovir (Zovirax)
Interaction Rating=Moderate Be cautious with this combination.
Taking chitosan with acyclovir might reduce the amount of acyclovir the body absorbs. This might reduce the effects of acyclovir.
Warfarin (Coumadin)
Interaction Rating=Moderate Be cautious with this combination.
Warfarin is a blood thinner. There is some concern that taking chitosan might increase the blood-thinning effects of warfarin. This could increase the risk for bruising or bleeding.
Interactions with herbs & supplements
Calcium: Chitosan might reduce how much calcium the body absorbs from supplements.
Magnesium: Chitosan might reduce how much magnesium the body absorbs from supplements.
Selenium: Chitosan might reduce how much selenium the body absorbs from supplements.
Vitamin A: Chitosan may reduce how much vitamin A the body absorbs from supplements.
Vitamin D: Chitosan may reduce how much vitamin D the body absorbs from supplements.
Vitamin E: Chitosan might reduce how much vitamin E the body absorbs from supplements.
Vitamin K: Chitosan may reduce how much vitamin K the body absorbs from supplements.
Magnesium: Chitosan might reduce how much magnesium the body absorbs from supplements.
Selenium: Chitosan might reduce how much selenium the body absorbs from supplements.
Vitamin A: Chitosan may reduce how much vitamin A the body absorbs from supplements.
Vitamin D: Chitosan may reduce how much vitamin D the body absorbs from supplements.
Vitamin E: Chitosan might reduce how much vitamin E the body absorbs from supplements.
Vitamin K: Chitosan may reduce how much vitamin K the body absorbs from supplements.
Interactions with foods
There are no known interactions with foods.
Products
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This monograph was last reviewed on 18/09/2023 10:00:00 and last updated on 29/08/2020 01:49:13. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
