Black mulberry
Black mulberry


Black mulberry (Morus nigra) is a plant found worldwide. The ripe berry, twigs, and root bark are used to make medicine. The ripe berry is also eaten.

Black mulberry fruit contains pectin, which might act as a laxative. Chemicals in black mulberry fruit and black mulberry twigs might have blood sugar lowering effects.

People use black mulberry for constipation, symptoms of menopause, runny nose, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse black mulberry with white mulberry. These are not the same.
When taken by mouth: Black mulberry fruit and the molasses made from the fruit is possibly safe when eaten as a food. The fruit is commonly used in foods, but there isn't enough reliable information to know if it is safe to use as a medicine. Black mulberry leaf is possibly safe when taken as a medicine, short-term. Black mulberry leaf powder has been used safely for up to 60 days.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if black mulberry is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Allergies: People who are allergic to fig might also be allergic to black mulberry.

Surgery: Black mulberry seems to lower blood sugar levels. It might interfere with blood sugar control during and after surgery. Stop using black mulberry at least 2 weeks before a scheduled surgery.


There is interest in using black mulberry for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of black mulberry might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

Medications for diabetes (Antidiabetes drugs)

Interaction Rating=Moderate Be cautious with this combination.

Black mulberry leaf might lower blood sugar levels. Taking black mulberry leaf along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Midazolam (Versed)

Interaction Rating=Moderate Be cautious with this combination.

The body breaks down midazolam to get rid of it. Black mulberry might slow the breakdown of midazolam. This might increase the effects and side effects of midazolam.

Interactions with herbs & supplements

Herbs and supplements that might lower blood sugar: Black mulberry leaf might lower blood sugar. Taking it with other supplements with similar effects might lower blood sugar too much. Examples of supplements with this effect include aloe, bitter melon, cassia cinnamon, chromium, and prickly pear cactus.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 16/11/2023 11:00:00 and last updated on 27/10/2020 00:59:22. Monographs are reviewed and/or updated multiple times per month and at least once per year.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. No reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. It is unlawful to download, store, or distribute content from this site.