Agaricus mushroom
Agaricus mushroom


Agaricus mushroom (Agaricus blazei) is a fungus that originated in Brazil. It now grows in China, Japan, Brazil, and the US. It's used as food and medicine.

Agaricus mushroom might strengthen the immune system, fight tumor growth, and work as an antioxidant.

People use agaricus mushroom for hay fever, cancer, heart disease, diabetes, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: Agaricus mushroom extract is possibly safe when used for up to 12 months. It's usually well-tolerated. Side effects might include stomach discomfort, diarrhea, and nausea.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if agaricus mushroom is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Liver disease: Agaricus mushroom might cause liver disease or make it worse. Don't use it if you have liver disease.

Surgery: Agaricus mushroom might lower blood sugar. This might interfere with blood sugar control during surgery. Stop using agaricus mushroom at least 2 weeks before a scheduled surgery.


There is interest in using agaricus mushroom for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

Agaricus mushroom extract has most often been used by adults in doses of 500 mg by mouth, three times daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

Medications for diabetes (Antidiabetes drugs)

Interaction Rating=Moderate Be cautious with this combination.

Agaricus mushroom might lower blood sugar levels. Taking agaricus mushroom along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Interactions with herbs & supplements

Herbs and supplements that might lower blood sugar levels: Agaricus mushroom might lower blood sugar. Taking it with other supplements with similar effects might lower blood sugar too much. Examples of supplements with this effect include aloe, bitter melon, cassia cinnamon, chromium, and prickly pear cactus.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 08/03/2024 11:00:00 and last updated on 24/07/2020 19:25:49. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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