- Silica contributes to the architecture and resilience of connective tissue by building bridges between elastin, collagen and mucopolysaccharides (such as chondroitin sulfate and other glycosaminoglycans), which aids in tissue stability and rigidity
- Sulfate is a structural component of many glycosaminoglycans, proteoglycans, glycolipids and glycoproteins and as such, acts similarly to silica as a stabiliser of connective tissue and contributes to its strength, elasticity and hydration
- In the extracellular matrix, sulfated proteoglycans have a strong negative charge attracting cations such as sodium, which in turn attracts water and provides hydration to connective tissue mesh and maintains its integrity
- Sodium and sulfate thus act together to maintain fluid balance within connective tissue
- Sulfur compounds are involved in phase II detoxification (conjugation), where they render metabolites more water-soluble, thereby inactivating them and facilitating their excretion in the bile, faeces or urine
- Sodium is required for bile production and is incorporated into the conjugation products of several bile salts
Dosage & warnings
Adults and children over 12 years: 1 tablet 3 times daily with meals
Children under 12 years: As professionally prescribed
Only take as directed.
This product is listed with the TGA - AustL 20309. The TGA publishes product info, including excipients under the "Other ingredients" subheading (not typically listed on the product label). Download the TGA public summary below.