Graviola (Annona muricata) is a small tree native to tropical regions. It makes edible fruit and has been used traditionally for parasite infections.

Graviola contains chemicals that might help fight against cancer, as well as bacteria, viruses, and parasites.

People use graviola for human papilloma virus (HPV), bacterial infections, cancer, and many other conditions, but there is no good scientific evidence to support these uses. It also might be unsafe.
When taken by mouth: Graviola is possibly unsafe. Taking larger amounts of the fruit or regularly drinking tea made from the leaves has been linked to movement disorders similar to Parkinson disease.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Do not use graviola. It is possibly unsafe when taken by mouth.

Parkinson disease: Graviola might make the symptoms of Parkinson disease worse.


There is interest in using graviola for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of graviola might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if Graviola interacts with any medicines. Before taking Graviola, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 31/07/2023 10:00:00 and last updated on 07/06/2018 18:09:42. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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