Genistein combined polysaccharide
Genistein combined polysaccharide


Genistein combined polysaccharide is a chemical that is made by fermenting soy with a certain type of mushroom called basidiomycetes.

Genistein combined polysaccharide is made up of genistein, a chemical found in soy, and a certain type of polysaccharide found in mushrooms. It might alter levels of some hormones in the body.

Genistein combined polysaccharide is used for prostate cancer, bladder cancer, and breast cancer, but there is no good scientific evidence to support any use.
When taken by mouth: There isn't enough reliable information to know if genistein combined polysaccharide is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn’t enough reliable information to know if genistein combined polysaccharide is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Genistein combined polysaccharide might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use genistein combined polysaccharide.


There is interest in using genistein combined polysaccharide for a number of purposes, but there isn’t enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn’t enough reliable information to know what an appropriate dose of genistein combined polysaccharide might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals


Interaction Rating=Moderate Be cautious with this combination.

Genistein combined polysaccharide contains a chemical called genistein. Genistein might slow down how quickly the body gets rid of caffeine. This might increase the effects of caffeine.

Interactions with herbs & supplements

Caffeine-containing herbs and supplements: Genistein combined polysaccharide might slow down the removal of caffeine from the body. Taking it with caffeine-containing herbs and supplements might increase the effects and side effects of caffeine. Examples of supplements that contain caffeine include black tea, coffee, green tea, guarana, and yerba mate.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 07/12/2023 11:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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