Dimethylglycine (dmg)
Dimethylglycine (dmg)


Dimethylglycine (DMG) is an amino acid, a building block for protein. The body needs dimethylglycine to function.

Dimethylglycine is an essential amino acid, which means that the body cannot make this chemical on its own. It must be consumed in the diet. It is found in grains and meats and can also be taken as a supplement.

People use dimethylglycine for aging, athletic performance, memory and thinking skills (cognitive function), and many other purposes, but there is no scientific evidence to support its use.
When taken by mouth: Dimethylglycine is possibly safe when used short-term, for up to 28 days. The safety of long-term use is unknown.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn’t enough reliable information to know if dimethylglycine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.


There is interest in using dimethylglycine for a number of purposes, but there isn’t enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn’t enough reliable information to know what an appropriate dose of dimethylglycine might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if Dimethylglycine (DMG) interacts with any medicines. Before taking Dimethylglycine (DMG), talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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