Diacylglycerol
Diacylglycerol

Background

Diacylglycerol is a compound found in small amounts in plant oils. Oils rich in diacylglycerol can be made in the lab and used to replace fats in the diet.

Diacylglycerol might work by increasing energy use and the breakdown of fat. Diacylglycerol-concentrated oils taste and look like regular fats and cooking oils.

People use diacylglycerol for obesity, diabetes, high levels of triglycerides in the blood, and other conditions, but there is no good scientific evidence to support most of these uses.
When taken by mouth: Diacylglycerol is likely safe for most people. It's usually well tolerated, but might cause some stomach upset similar to other cooking oils.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Diacylglycerol is likely safe when consumed in foods. There isn't enough reliable information to know if diacylglycerol is safe to use in larger amounts when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Obesity. Taking diacylglycerol by mouth seems to improve weight loss in overweight or obese adults.
There is interest in using diacylglycerol for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

Diacylglycerol is a compound naturally found in small amounts in plant oils. Oils such as soybean and rapeseed can be changed to include higher concentrations of diacylglycerol to be used as replacement cooking oils. It's most often been used by adults in doses of 10-20 grams by mouth daily for up to 1 year. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

It is not known if Diacylglycerol interacts with any medicines. Before taking Diacylglycerol, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 12/04/2024 10:00:00 and last updated on 18/11/2020 03:07:15. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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