Corkwood tree
Corkwood tree


Corkwood tree (Duboisia myoporoides) is native to Australia. It's grown as a source of certain chemicals, including scopolamine and atropine, which are used as drugs.

The chemicals in corkwood tree can affect the central nervous system and cause serious side effects. The cured and rolled leaves (quids) are sometimes chewed.

People use corkwood tree quids for hunger, pain, tiredness, and other conditions, but there is no good scientific evidence to support these uses. It might also be unsafe.

Don't confuse corkwood tree with phellodendron, which is sometimes called cork tree. These are not the same.
When taken by mouth: Corkwood tree is likely unsafe. It contains chemicals that can cause many serious side effects, including convulsions, coma, and death.

Special Precautions & Warnings:

Pregnancy and breast-feeding: It's likely unsafe for anyone, including those pregnant or breast-feeding, to take corkwood tree. Avoid use.


There is interest in using corkwood tree for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of corkwood tree might be. It's also likely unsafe. Speak with a healthcare provider before use.

Interactions with pharmaceuticals

Drying medications (Anticholinergic drugs)

Interaction Rating=Moderate Be cautious with this combination.

Corkwood tree can block a chemical in the body called acetylcholine, which has many important functions. Some medications, called anticholinergic drugs, also block acetylcholine. There is some concern that taking them together might increase the risk for confusion, blurred vision, decreased sweating, and increased heart rate.

Interactions with herbs & supplements

Herbs that affect the brain and heart (anticholinergic herbs): Corkwood tree might block a chemical in the body called acetylcholine. Acetylcholine plays a big part in many important body functions. There is some concern that taking corkwood tree along with other supplements with similar effects might cause increase the risk for blurred vision, confusion, increased sweating, and increased heart rate. Examples of supplements with this effect include angel's trumpet, belladonna, bitter yam, jimson weed, and scopolia.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 16/11/2023 11:00:00 and last updated on 01/03/2022 08:21:10. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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