Collagen peptides
Collagen peptides


Collagen peptides are very small pieces of protein from animal collagen. Collagen is one of the materials that makes up cartilage, bone, and skin.

Collagen peptides are made by breaking down whole collagen proteins into smaller pieces. When taken by mouth, collagen peptides seem to build up in the skin and cartilage. This might help improve some skin and joint conditions.

Collagen peptides are used for aging skin and osteoarthritis. They are also used for osteoporosis, brittle nails, muscle strength, and many other purposes, but there is no good scientific evidence to support most of these uses.

Don't confuse collagen peptides with collagen type I (native), collagen type II (native), or gelatin.
When taken by mouth: Collagen peptides are possibly safe. Collagen peptides have been safely used in doses up to 10 grams daily for up to 5 months. Side effects are rare.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if collagen peptides are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.


NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Aging skin. Taking collagen peptides by mouth seems to improve skin hydration and skin elasticity in older people. It might also help reduce wrinkles, but it's not clear if it helps enough to be noticeable.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
  • Muscle strength. Taking collagen peptides by mouth does not seem to improve leg muscle strength. However, collagen peptides may improve hand-grip strength.
There is interest in using collagen peptides for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Insufficient evidence Effectiveness definitions

Dosing & administration

Collagen peptides have most often been used by adults in doses of 2.5-10 grams daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

It is not known if Collagen Peptides interacts with any medicines. Before taking Collagen Peptides, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 16/11/2023 11:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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