Chenopodium oil
Chenopodium oil


Chenopodium oil is made from the chenopodium plant (Dysphania ambrosioides), which is also known as epazote. It grows in Central and South America.

Chenopodium oil contains high amounts of a toxic chemical called ascaridole. The amount of ascaridole found in the oil depends on the plant part used, the season, and where the plant was grown. Ascaridole is thought to paralyze roundworms, hookworms, and some tapeworms.

People use chenopodium oil for parasite infections in the intestine and other conditions, but there is no good scientific evidence to support these uses. Using chenopodium oil can also be unsafe. It has been linked with serious side effects, including death.

Don't confuse chenopodium oil, which is also called wormseed, with wormseed and wormwood. These are not the same.
When taken by mouth: Chenopodium oil is unsafe. It contains the chemical ascaridole, which is toxic. Potential side effects include dizziness, skin irritation, vomiting, deafness, paralysis, liver damage, and death.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Chenopodium oil is unsafe when taken by mouth while pregnant or breast-feeding. It contains toxic chemicals.


There is interest in using chenopodium oil for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of chenopodium oil might be. It contains toxic chemicals that are unsafe. Speak with a healthcare provider before use.

Interactions with pharmaceuticals

Medications that increase sensitivity to sunlight (Photosensitizing drugs)

Interaction Rating=Moderate Be cautious with this combination.

Some medications might make the skin more sensitive to sunlight. Chenopodium oil might also make the skin more sensitive to sunlight. Using these products together might increase the risk of sunburn, blistering, or rashes when the skin is exposed to sunlight. Be sure to wear sunblock and protective clothing when spending time in the sun.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 31/05/2023 10:00:00 and last updated on 26/12/2012 18:08:46. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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