
Bromelain
Scientific names: Bromelain
Family: Bromeliaceae
Alternate names: Bromelaine, Bromélaïne, Bromelains, Bromelainum, Bromelin, Bromelina, Broméline, Enzyme d'Ananas, Pineapple Enzyme, Pineapple Fruit Bromelain
Actions: Anti-inflammatory, Cytotoxic, Dermatological, Gastrointestinal, Hematologic, Immunomodulatory
Background
Bromelain is a type of enzyme called a proteolytic enzyme. It is found in pineapple juice and in the pineapple stem.
Bromelain causes the body to make substances that fight pain and swelling. Bromelain also contains chemicals that seem to interfere with tumor cells and slow blood clotting.
People use bromelain for muscle soreness, pain, burns, kidney stones, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse bromelain with other proteolytic enzymes (proteases), such as chymotrypsin, ficin, papain, serrapeptase, or trypsin. These are not the same.
Bromelain causes the body to make substances that fight pain and swelling. Bromelain also contains chemicals that seem to interfere with tumor cells and slow blood clotting.
People use bromelain for muscle soreness, pain, burns, kidney stones, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse bromelain with other proteolytic enzymes (proteases), such as chymotrypsin, ficin, papain, serrapeptase, or trypsin. These are not the same.
Safety Safety definitions
When taken by mouth: Bromelain is possibly safe for most people. Doses of up to 240 mg daily have been used safely for up to one year. Bromelain might cause some side effects, including diarrhea and stomach upset.
When applied to the skin: Bromelain is possibly safe. It might cause allergic reactions in some people.
Allergies: People with other allergies might also be allergic to bromelain. Use cautiously if you are allergic to pineapple, latex, ragweed, Echinacea, chrysanthemums, marigolds, daisies, wheat, celery, papain, carrot, fennel, cypress pollen, grass pollen, or other plants.
Surgery: Bromelain might increase the risk of bleeding during and after surgery. Stop using bromelain at least 2 weeks before a scheduled surgery.
When applied to the skin: Bromelain is possibly safe. It might cause allergic reactions in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if bromelain is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Allergies: People with other allergies might also be allergic to bromelain. Use cautiously if you are allergic to pineapple, latex, ragweed, Echinacea, chrysanthemums, marigolds, daisies, wheat, celery, papain, carrot, fennel, cypress pollen, grass pollen, or other plants.
Surgery: Bromelain might increase the risk of bleeding during and after surgery. Stop using bromelain at least 2 weeks before a scheduled surgery.
Effectiveness
Effective Effectiveness definitions
There is interest in using bromelain for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
Bromelain has most often been used by adults in doses of 40-400 mg by mouth daily for up to 13 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Antibiotics (Tetracycline antibiotics)
Interaction Rating=Minor Be watchful with this combination.
Taking bromelain might increase how much antibiotic the body absorbs. Taking bromelain along with some antibiotics called tetracyclines might increase the effects and side effects of these antibiotics.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Moderate Be cautious with this combination.
Bromelain might slow blood clotting. Taking bromelain along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Interactions with herbs & supplements
Herbs and supplements that might slow blood clotting: Bromelain might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
Zinc: Metals such as zinc might slow down the activity of bromelain in the body. But this isn't likely to be a big concern.
Zinc: Metals such as zinc might slow down the activity of bromelain in the body. But this isn't likely to be a big concern.
Interactions with foods
Taking bromelain after eating potato or soy might slow down bromelain's effects in the body.
Products
View all productsPer 7 g (Pineapple):
- Ananas comosus (Pineapple)
- Ananas comosus (Bromelain) 70 mg
- Spinacia oleracea (Spinach)
- Medicago sativa
- Brassica oleracea (leaf) powder (Kale)
- Wheatgrass powder
- L-glutamine 980 mg
- Carica papaya juice dry
- Natural pineapple flavour
- Citrus limon (juice) (Lemon)
- Citric acid anhydrous
- Natural vanilla flavour
- Lactobacillus acidophilus 28 mg
- Lactobacillus rhamnosus 14 mg
- Bifidobacterium longum 14 mg
- Bifidobacterium lactis 7 mg
- Curcuma longa ext.
- Rosmarinus officinalis ext.
- Stevia rebaubiana
$72.95
Per 10 g:
- Ananas comosus (Pineapple) 240 mg
- Ananas comosus (Bromelain) 65 mg
- Arthrospira platensis (Spirulina) 1 g
- Chlorella pyrenoidosa powder 333 mg
- Wheatgrass powder 333 mg
- Inulin (Dietary fibre) 800 mg
- Lactobacillus acidophilus 5 billion CFU
- Bifidobacterium bifidum 3 billion CFU
- Bifidobacterium lactis 5 billion CFU
- Bifidobacterium longum 1 billion CFU
- Cynara scolymus powder 500 mg
- Hordeum vulgare 200 mg
- Malus (Apple) 200 mg
- Brassica oleracea (leaf & sprout) powder (Kale) 100 mg
- Spinacia oleracea (Spinach) 67 mg
- Beta glucan 50 mg
- Resveratrol 10 mg
- Linum usitatissimum (seed) (Flaxseed) 400 mg
- Oryza sativa (Rice bran) 500 mg
- Pea protein isolate 1 g
- R-alpha lipoic acid 67 mg
- Thiamine hydrochloride (Vitamin B1) 400 µg
- Niacinamide (Vitamin B3) 5.3 mg
- Pyridoxine hydrochloride (Vitamin B6) 567 µg
- Riboflavin (Vitamin B2) 434 µg
- Pantothenic acid (Vitamin B5) 1.7 mg
- Cyanocobalamin (Vitamin B12) 0.8 µg
- Ergocalciferol (Vitamin D) 3.8 µg
- Ascorbic acid (Vitamin C) 333 mg
- d-alpha-Tocopheryl acid succinate (Vitamin E) 100 mg
- Ubidecarenone (Coenzyme Q10) 8 mg
- Copper gluconate 225 µg
- Potassium phosphate - dibasic 104 mg
- Folic acid 67 µg
- Biotin 10 µg
- Silica - colloidal anhydrous 14 mg
- Magnesium citrate 42 mg
- Zinc amino acid chelate 10 mg
- Chromium picolinate 10 µg
- Calcium citrate 132 mg
- Manganese amino acid chelate 1.4 mg
- Selenomethionine (Selenium) 30 µg
- Beta-carotene (Carotenoids) 1.7 mg
- Citrus bioflavonoids (Hesperidin) 500 mg
- Citric acid anhydrous 150 mg
- Rosmarinus officinalis powder 68 mg
- Taraxacum officinale ext. 33 mg
- Vaccinium myrtillus powder 200 mg
- Glycyrrhiza glabra powder 67 mg
- Crataegus monogyna ext. 29 mg
- Astragalus membranaceus ext. 67 mg
- Vitis vinifera ext. 67 mg
- Camellia sinensis ext. 67 mg
- Ganoderma lucidum powder 21 mg
- Lentinula edodes powder 21 mg
- Aloe barbadensis ext. 500 mg
- Zingiber officinale powder 67 mg
- Eleutherococcus senticosus ext. 1 g
- Centella asiatica ext. 67 mg
- Withania somnifera ext. 67 mg
- Silybum marianum ext. 67 mg
- Arctium lappa ext. 21 mg
- Rosa canina powder 168 mg
- Lycium barbarum 33 mg
- Beta vulgaris (root) powder (Beetroot) 167 mg
- Daucus carota powder (Carrot) 83 mg
- Carica papaya (Papain) 250 mg
- Lecithin 725 mg
- Laminaria digitara (Kelp) 8 mg
- Natural vanilla flavour
- Natural pineapple flavour
- Thaumatin
- Stevia rebaubiana
- Luo Han Guo (fruit) ext. (Monk fruit)
- Xanthan gum
- Brassica oleracea var. italica powder 150 mg
- Malpighia glabra ext. 267 mg
- Theobroma cacao powder 100 mg
1 kg
RRP: $226.40$147.16Save: 35%
Per 5 g:
- Ananas comosus (Pineapple)
- Ananas comosus (Bromelain)
- Inulin (Dietary fibre)
- Marine collagen peptides 250 mg
- Lepidium meyenii (root) powder
- Lactobacillus rhamnosus (LR-32)
- Bifidobacterium longum (BL-05)
- Zinc
- Cannabis sativa powder 520 mg
- Arthrospira platensis (Spirulina) 370 mg
- Linum usitatissimum (seed) flour (Flaxseed) 250 mg
- Wheatgrass powder
- Sunflower lecithin
- Citrus limon (juice) (Lemon)
- Ascorbic acid (Vitamin C)
- Euterpe oleracea (berry) ext. (Acai)
- Chlorella pyrenoidosa powder
- Lycopersicon esculentum (Tomato)
- Apple pectin
- Beta vulgaris (root) powder (Beetroot)
- Citric acid anhydrous
- Citrullus lanatus (Watermelon)
- Fragaria ananassa (juice) powder (Strawberry)
- Garcinia mangostana (fruit) powder
- Punica granatum juice dry
- Carica papaya (fruit) powder
- Vaccinium macrocarpon (fruit) powder
- Natural vanilla flavour
- Lycium barbarum (fruit)
- Aristotelia chilensis (Maqui berry)
- Silybum marianum powder
- Astragalus membranaceus (root) powder
- Equisetum arvense (herb) powder
- Laminaria digitara (Kelp)
- Silica - colloidal anhydrous
- Daucus carota powder (Carrot)
- Camellia sinensis powder
- Withania somnifera (root) powder
- Eleutherococcus senticosus (root) powder
- Echinacea purpurea (root) powder
- Melissa officinalis powder
- Taraxacum officinale (leaf) powder
- Zingiber officinale (root) powder
- Rosa canina powder
- Vaccinium myrtillus (fruit) powder
- Ulmus rubra (bark) powder
- Mushroom powder
- Kakadu plum powder
- Calcium pantothenate (Vitamin B5)
- Panax ginseng powder
- Curcuma longa (root) powder
- Backhousia citriodora (leaf)
- Thaumatin
- Protease
- Phyllanthus emblica (fruit) powder
- Morindae officinalis (fruit) powder
- Marine algae
- Malpighia glabra (fruit) powder
- Medicago sativa 200 mg
- Sambucus nigra (fruit)
- Vaccinium corymbosum (fruit) powder
- Hordeum vulgare powder 200 mg
- Salvia hispanica (seed) powder
RRP: $39.95$33.96Save: 15%
Practitioner product
Per capsule:
- Ananas comosus (Bromelain) 1500000 PU
- Amylase enzyme 10000 DUAA
- Protease 60000 HUT
- Lipase 400 LipU
- Tilactase 1500 ALU
- Cellulase 125 CU
- Gentiana lutea ext. 120 mg
RRP: $48.95$34.27Save: 30%
RRP: $49.95$44.96Save: 10%
Per capsule:
- Ananas comosus (Bromelain) 218000 PU
- Carica papaya (Papain) 235000 PU
- Aspergillus oryzae (Kōji mould) 5.7 mg equiv. amylase 750 DU
- Aspergillus oryzae (Kōji mould) 4.75 mg equiv. protease 3790 HUT
- Rhizopus oryzae (Microfungus) 9.4 mg equiv. lipase 525 LipU
- Lactobacillus acidophilus (MED 27 & MED 28) 5 billion CFU
- Lactobacillus rhamnosus (Med 26) 2.5 billion CFU
- Bifidobacterium bifidum (MED 11) 125 million CFU
- Bifidobacterium animalis ssp. lactis (MED 13) 1.125 billion CFU
Practitioner product
Per 5 g (Cucumber Lime):
- Ananas comosus (Bromelain) 350 GDU
- Brassica oleracea var. italica powder 250 mg
- Arthrospira platensis (Spirulina) 100 mg
- Cordyceps sinensis 105 mg
- Lentinula edodes 100 mg
- Trametes versicolor 70 mg
- Astragalus membranaceus 100 mg
- Camellia sinensis 500 mg
- Grifola frondosa 125 mg
- Spinacia oleracea (Spinach) 175 mg
- Brassica oleracea (leaf) powder (Kale) 175 mg
- Chlorella vulgaris powder 175 mg
- Nasturtium officinale 160 mg
- Apium graveolens powder 110 mg
- Pleurotus eryngii 100 mg
- Lipase 750 LipU
- Protease 1000 DU
- Carica papaya (Papain) 40 mg
- L-glutamine 500 mg
- Bacillus coagulans (LactoSpore®) 4 billion CFU
- Lactobacillus rhamnosus 750 million CFU
- Saccharomyces cerevisiae (boulardii) (SB) 500 million CFU
- Quercetin 100 mg
- Taraxacum officinale 100 mg
- Coriandrum sativum 80 mg
- Zingiber officinale 50 mg
- Rosmarinus officinalis 50 mg
- Origanum vulgare powder 50 mg
- Natural flavours
- Stevia rebaubiana ext.
- Eleutherococcus senticosus 100 mg
- Citric acid anhydrous
150 g Cucumber Lime
RRP: $59.95$53.96Save: 10%
RRP: $51.95$36.37Save: 30%
Practitioner product
Per 3.1 g (Lime):
- Ananas comosus (Bromelain) 1.5 million PU
- Quercetin dihydrate 447.7 mg equiv. quercetin 400 mg
- Rutin (Rutoside) 500 mg
- d-alpha-Tocopheryl acid succinate 200 mg equiv. vitamin E 242 IU
- Magnesium ascorbate monohydrate (Vitamin C) 952.7 mg equiv. ascorbic acid 850 mg
- Zinc gluconate 27.93 mg equiv. zinc 4 mg
- Calcium pantothenate (Vitamin B5) 109 mg equiv. pantothenic acid 99.9 mg
- Selenomethionine 32.24 μg equiv. selenium 13 μg
- Retinol acetate (Vitamin A) 0.884 mg equiv. vitamin A 750 μgRE equiv. vitamin A 2500 IU
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Per 5 g (Chocolate Malt):
- Ananas comosus (Bromelain) 150 mg
- Hordeum vulgare (Barley)
- Green banana starch 250 mg
- Arthrospira platensis (Spirulina)
- Quercetin 200 mg
- Brassica oleracea (Broccoli)
- Apple pectin 50 mg
- Larix occidentalis (arabinogalactan) (Larch) 250 mg
- Bacillus coagulans (LactoSpore®) 25 mg
- Punica granatum
- Macrocystis pyrifera (Ocean kelp)
- Brassica oleracea (leaf & sprout) powder (Kale)
- Spinacia oleracea (Spinach)
- Daucus carota powder (Carrot)
- Brassica oleracea var. viridis
- Palmaria palmata (Dulse)
- Chlorella vulgaris powder
- Apium graveolens (seed) powder
- Petroselinum crispum
- Citrus bioflavonoids extract 150 mg
- Myrciaria dubia (fruit) powder (Camu Camu)
- Malpighia glabra
- Blueberry flavour
- Zingiber officinale
- Kakadu plum powder
- Cocoa powder
- Natural flavours
- Pink Himalayan crystal salt
- Origanum vulgare oil
- Thymus vulgaris oil
- Syzygium aromaticum oil
- Mentha x piperita oil
- N-acetyl glucosamine (NAG) 125 mg
- Stevia rebaubiana
- Zinc citrate 7.5 mg
- Polyphenolic fulvic minerals (Cell Charge™) 50 mg
150 g Chocolate Malt
RRP: $59.99$52.80Save: 12%
Per capsule:
- Ananas comosus (Bromelain) 100 mg
- Curcuma longa ext. 23.08 mg
- Ascorbic acid (Vitamin C) 40 mg
- Copper gluconate 1.79 mg equiv. copper 250 μg
- Quercetin dihydrate 100 mg
- Carica papaya (Papain) 20 mg
- Citrus bioflavonoids (Hesperidin) 50 mg
- Rutin (Rutoside) 50 mg
- d-alpha-Tocopheryl acid succinate 20.66 mg equiv. vitamin E 25 IU
- R,S-alpha lipoic acid 20 mg
- Manganese amino acid chelate 5 mg equiv. manganese 500 μg
- Zinc amino acid chelate 10 mg equiv. zinc 2 mg
- Cyanocobalamin (Vitamin B12) 100 μg
- Folic acid 160 μg
- Pyridoxine hydrochloride (Vitamin B6) 15 mg equiv. pyridoxine 12.34 mg
- Riboflavin (Vitamin B2) 50 mg
Practitioner product
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Per tablet:
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This monograph was last reviewed on 31/07/2023 10:00:00 and last updated on 20/06/2018 21:08:31. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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