Black nightshade
Black nightshade


Black nightshade (Solanum nigrum) is a plant with a musk-like smell when wilting. It contains a chemical that can be toxic when consumed.

Black nightshade contains a chemical called solanine which is poisonous to humans. The green fruits contain the highest amounts of solanine and therefore are the most toxic parts of the plant.

People use black nightshade for stomach irritation, cramps, spasms, pain, nervousness, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: Black nightshade unripe berries and leaves are likely unsafe. These contain a toxic chemical called solanine. At lower doses, they can cause nausea, vomiting, and other side effects. At higher doses, they can cause severe poisoning, which can lead to death.

There isn't enough reliable information to know if the ripe berries of black nightshade are safe or what the side effects might be.

When applied to the skin: There isn't enough reliable information to know if black nightshade is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: It's likely unsafe to use black nightshade while pregnant. It might cause birth defects.


There is interest in using black nightshade for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

Black nightshade can be poisonous. There isn't enough reliable information to know what an appropriate dose of black nightshade might be. Consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if Black Nightshade interacts with any medicines. Before taking Black Nightshade, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 29/06/2023 10:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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