Agave (Agave americana) is a plant found in southwestern US and Central and South America. It has thick, rigid leaves that form the shape of a rosette.

Some chemicals in agave might reduce swelling and prevent the growth of some cancer cells. Some chemicals might also cause the uterus to contract.

People use agave for constipation, cancer, male-pattern baldness, diarrhea, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: There isn't enough reliable information to know if agave is safe or what the side effects might be.

When applied to the skin: Fresh agave is possibly unsafe. Exposure to the fresh agave plant may cause swelling and redness, skin sores, and swelling of small blood vessels within minutes to hours of exposure. The sap appears to be the most irritating part of the plant.

Special Precautions & Warnings:

Pregnancy:Taking agave by mouth during pregnancy is likely unsafe. It might stimulate the uterus and cause contractions.

Breast-feeding: There isn't enough reliable information to know if agave is safe to use when breast-feeding. Stay on the safe side and avoid use.


There is interest in using agave for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
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Dosing & administration

There isn't enough reliable information to know what an appropriate dose of agave might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if this product interacts with any medicines.

Before taking this product, talk with your health professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods. has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 07/12/2023 11:00:00 and last updated on 01/01/2021 03:03:20. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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