Saccharomyces boulardii
Scientific names: Saccharomyces cerevisiae var boulardii
Family: Saccharomycetaceae
Alternate names: Probiotic, Probiotique, Saccharomyces, Saccharomyces Boulardii CNCM I-745, Saccharomyces Boulardii HANSEN CBS 5926, Saccharomyces Boulardii Lyo CNCM I-745, Saccharomyces Boulardius, Saccharomyces Cerevisiae Boulardii, Saccharomyces Cerevisiae (Boulardii), Saccharomyces Cerevisiae (Boulardii) HANSEN CBS 5926, Saccharomyces Cerevisiae HANSEN CBS 5926, S. Boulardii, SCB
Actions: Anti-amoebae activity, Effects in patients with Crohn's disease, Gastrointestinal
Background
Saccharomyces boulardii (S. boulardii) is a type of probiotic ("friendly" organism). It's a yeast that is actually a strain of Saccharomyces cerevisiae.
"Friendly" organisms such as S. boulardii can help fight off "bad" organisms that might cause diseases. S. boulardii is different from other strains of S. cerevisiae, commonly known as brewer's yeast and baker's yeast.
People commonly use S. boulardii for treating and preventing diarrhea, including rotaviral diarrhea in children. It's also used for other types of diarrhea, acne, a digestive tract infection that can lead to ulcers, and many other conditions, but there is no good scientific evidence to support many of its other uses. There is also no good evidence to support using S. boulardii for COVID-19.
Don't confuse S. boulardii with other probiotics, or with fermented food products such as fermented milk, kefir, or yogurt. These are not the same.
"Friendly" organisms such as S. boulardii can help fight off "bad" organisms that might cause diseases. S. boulardii is different from other strains of S. cerevisiae, commonly known as brewer's yeast and baker's yeast.
People commonly use S. boulardii for treating and preventing diarrhea, including rotaviral diarrhea in children. It's also used for other types of diarrhea, acne, a digestive tract infection that can lead to ulcers, and many other conditions, but there is no good scientific evidence to support many of its other uses. There is also no good evidence to support using S. boulardii for COVID-19.
Don't confuse S. boulardii with other probiotics, or with fermented food products such as fermented milk, kefir, or yogurt. These are not the same.
Safety Safety definitions
When taken by mouth: S. boulardii is likely safe when used for up to 15 months. It can cause gas in some people.
Children: S. boulardii is possibly safe for children when taken by mouth appropriately. But diarrhea in children should be evaluated by a healthcare professional before using S. boulardii.
Elderly: Older adults might have an increased risk of fungal infection when taking S. boulardii. Stay on the safe side and avoid use.
Digestive tract disease: S. boulardii has caused fungal infections in people with diseases of the digestive tract. If you have a digestive tract disease, talk with your healthcare provider before taking S. boulardii.
Weakened immune system: S. boulardii has caused fungal infections in people with weakened immune systems. In many cases, the infection was due to a catheter becoming contaminated. If you have a weakened immune system, talk with your healthcare provider before taking S. boulardii.
Yeast allergy: People with yeast allergy can be allergic to products containing S. boulardii. Stay on the safe side and avoid these products.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if S. boulardii is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: S. boulardii is possibly safe for children when taken by mouth appropriately. But diarrhea in children should be evaluated by a healthcare professional before using S. boulardii.
Elderly: Older adults might have an increased risk of fungal infection when taking S. boulardii. Stay on the safe side and avoid use.
Digestive tract disease: S. boulardii has caused fungal infections in people with diseases of the digestive tract. If you have a digestive tract disease, talk with your healthcare provider before taking S. boulardii.
Weakened immune system: S. boulardii has caused fungal infections in people with weakened immune systems. In many cases, the infection was due to a catheter becoming contaminated. If you have a weakened immune system, talk with your healthcare provider before taking S. boulardii.
Yeast allergy: People with yeast allergy can be allergic to products containing S. boulardii. Stay on the safe side and avoid these products.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
- Diarrhea. Taking S. boulardii by mouth can reduce how long diarrhea lasts in children. It's not clear if it helps children with longer-lasting diarrhea or if it helps adults.
Possibly effective Effectiveness definitions
- Diarrhea in people taking antibiotics (antibiotic-associated diarrhea). Taking S. boulardii by mouth can help prevent diarrhea in adults and children being treated with antibiotics.
- Infection of the gastrointestinal tract by bacteria called Clostridioides difficile. Taking S. boulardii by mouth seems to help prevent diarrhea from C. difficile infection. Taking it along with antibiotics also seems to help prevent this infection from coming back.
- A digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori). Taking S. boulardii by mouth along with standard H. pylori treatment helps prevent side effects such as diarrhea and nausea that occur with standard H. pylori treatment. But it isn't clear if taking S. boulardii helps these standard treatments to work better.
- A serious intestinal disease in premature infants (necrotizing enterocolitis or NEC). Most research shows that giving S. boulardii by mouth to preterm infants prevents NEC.
- Diarrhea caused by rotavirus. Taking S. boulardii by mouth seems to reduce how long diarrhea lasts in children with diarrhea caused by rotavirus.
- Travelers' diarrhea. Taking S. boulardii by mouth seems to reduce the risk of developing diarrhea while traveling.
Possibly ineffective Effectiveness definitions
- Blood infection (sepsis). Giving S. boulardii to preterm infants by mouth does not prevent sepsis.
Dosing & administration
In adults, S. boulardii has most often been taken by mouth in doses of 500-1000 mg (about 10-20 billion colony-forming units) daily for 4 weeks. In children, S. boulardii has most often been taken by mouth in doses of 250-500 mg (about 5-10 billion colony-forming units) for up to 4 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Medications for fungal infections (Antifungals)
Interaction Rating=Minor Be watchful with this combination.
S. boulardii is a fungus. Medications for fungal infections help reduce fungus in and on the body. Taking S. boulardii with medications for fungal infections can reduce the effects of S. boulardii.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
View all products
Per capsule:
- Saccharomyces cerevisiae (boulardii) (SB) 10 billion CFU
- Lactobacillus plantarum (LP01) 2.5 billion CFU
- Bifidobacterium breve (BB-03) 2.5 billion CFU
- Bifidobacterium animalis ssp. lactis (BS-01) 2.5 billion CFU
- Bifidobacterium animalis ssp. lactis (BI-04) 2 billion CFU
- Bifidobacterium animalis ssp. lactis (HN019) 2 billion CFU
RRP: $49.95$37.46Save: 25%
RRP: $58.95$40.08Save: 32%
RRP: $54.00$37.80Save: 30%
RRP: $81.95$55.73Save: 32%
RRP: $29.00$24.65Save: 15%
Per 3 g:
- Saccharomyces cerevisiae (boulardii) (SB) 2.5 billion CFU
- Lactobacillus rhamnosus GG 10 billion CFU
- Bifidobacterium animalis ssp. lactis (HN019) 2 billion CFU
- Bifidobacterium lactis (BI-04) 2 billion CFU
- Lactobacillus plantarum (LP-115) 1.5 billion CFU
- Lactobacillus paracasei (LPC-37) 1 billion CFU
- Lactobacillus acidophilus (LA-14) 1 billion CFU
- Lactobacillus casei (LC-11) 900 million CFU
- Streptococcus thermophilus (ST-21) 600 million
- Bifidobacterium infantis (BI-26) 300 million CFU
- Bifidobacterium bifidum (BB-06) 200 million CFU
- Lactobacillus delbrueckii ssp. bulgaricus (LB-87) lactis 200 million CFU
- Lactobacillus brevis (LBR-35) 200 million CFU
- Lactobacillus salivarius (LS-33) 200 million CFU
- Bifidobacterium breve (BB-18) 200 million CFU
- Bifidobacterium longum (BI-05) 200 million CFU
- Lactobacillus gasseri (LG-36) 100 million CFU
- Lactobacillus reuteri (KP-1E1) 100 million CFU
- Actinidia chinensis powder 555 mg
RRP: $77.00$69.30Save: 10%
Per capsule:
- Saccharomyces cerevisiae (boulardii) (SB) 833.3 million CFU
- Lactobacillus rhamnosus GG 3.33 billion CFU
- Bifidobacterium animalis ssp. lactis (HN019) 667 million CFU
- Bifidobacterium lactis (BI-04) 667 million CFU
- Lactobacillus plantarum (LP-115) 500 million CFU
- Lactobacillus paracasei (LPC-37) 333.3 million CFU
- Lactobacillus acidophilus (LA-14) 333.3 million CFU
- Lactobacillus casei (LC-11) 300 million CFU
- Streptococcus thermophilus (ST-21) 200 million CFU
- Bifidobacterium infantis (BI-26) 100 million CFU
- Bifidobacterium bifidum (BB-06) 66.7 million CFU
- Lactobacillus delbrueckii ssp. bulgaricus (LB-87) lactis 66.7 million CFU
- Lactobacillus brevis (LBR-35) 66.7 million CFU
- Lactobacillus salivarius (LS-33) 66.7 million CFU
- Bifidobacterium breve (BB-18) 66.7 million CFU
- Bifidobacterium longum (BL-05) 66.7 million CFU
- Lactobacillus gasseri (LG-36) 33.3 million CFU
- Lactobacillus reuteri (KP-1E1) 33.3 million CFU
- Actinidia chinensis powder 185 mg
RRP: $77.50$69.75Save: 10%
Per 5 g (Granny Smith):
- Saccharomyces cerevisiae (boulardii) (SB) 500 million CFU
- Brassica oleracea var. italica powder 250 mg
- Arthrospira platensis (Spirulina) 100 mg
- Cordyceps sinensis 105 mg
- Lentinula edodes 100 mg
- Trametes versicolor 70 mg
- Astragalus membranaceus 100 mg
- Camellia sinensis 500 mg
- Grifola frondosa 125 mg
- Spinacia oleracea (Spinach) 175 mg
- Brassica oleracea (leaf) powder (Kale) 175 mg
- Chlorella vulgaris powder 175 mg
- Nasturtium officinale 160 mg
- Apium graveolens powder 110 mg
- Pleurotus eryngii 100 mg
- Lipase 750 LipU
- Protease 1000 DU
- Ananas comosus (Bromelain) 350 GDU
- Carica papaya (Papain) 40 mg
- L-glutamine 500 mg
- Bacillus coagulans (LactoSpore®) 4 billion CFU
- Lactobacillus rhamnosus 750 million CFU
- Quercetin 100 mg
- Taraxacum officinale 100 mg
- Coriandrum sativum 80 mg
- Zingiber officinale 50 mg
- Rosmarinus officinalis 50 mg
- Origanum vulgare powder 50 mg
- Natural flavours
- Stevia rebaubiana ext.
- Eleutherococcus senticosus 100 mg
- Malic acid
150 g Granny Smith
RRP: $59.95$53.96Save: 10%
Per capsule:
- Saccharomyces cerevisiae (boulardii) (SB) 100 million CFU
- Lactobacillus rhamnosus GG 5 billion CFU
- Lactobacillus salivarius (LS-33) 300 million CFU
- Lactobacillus rhamnosus (HN001) 6 billion CFU
- Lactobacillus acidophilus (LA-14) 300 million CFU
- Bifidobacterium animalis spp. lactis (HN019) 2 billion CFU
- Bifidobacterium lactis (BI-04) 200 million CFU
- Lactobacillus paracasei (LPC-37) 24.9 billion CFU
- Lactobacillus plantarum (LP-115) 15 billion CFU
- Lactobacillus gasseri (LG-36) 200 million CFU
- Streptococcus thermophilus (ST-21) 1 billion CFU
RRP: $83.45$58.41Save: 30%
Out of stock with supplier
Restock unknown
RRP: $45.95$31.24Save: 32%
Per 2 g (Honey Lemon):
- Saccharomyces cerevisiae (boulardii) (SB) 440 mg
- Ascorbic acid (Vitamin C) 900 mg
- Zinc citrate 32.26 mg equiv. zinc 10 mg
- Calcium ascorbate dihydrate (Vitamin C) 219 mg equiv. ascorbic acid 180 mg
- Kakadu plum powder 20 mg
- Cholecalciferol (Vitamin D3) 12.5 µg equiv. vitamin D 500 IU
- Olea europaea ext. 50 mg
RRP: $37.74$30.94Save: 18%
Discontinued by Melrose
Per 8 g:
- Saccharomyces cerevisiae (boulardii) (SB) 200 mg
- Arthrospira platensis (Spirulina) 1.68 g
- Wheatgrass powder 1.12 g
- Medicago sativa powder 160 mg
- Hordeum vulgare powder 160 mg
- Chlorella pyrenoidosa powder
- Spinacia oleracea (Spinach) 80 mg
- Brassica oleracea (leaf) powder (Kale) 80 mg
- Brassica oleracea var. acephala (sprout) powder
- Inulin (Dietary fibre)
- Pea (fibre) sprouted
- Lepidium meyenii (root) powder
- Tremella fuciformis powder 200 mg
- Lucuma
- Oryza sativa (Brown rice protein)
- Lentinula edodes powder 160 mg
- Quinoa (sprout) powder
- Malpighia glabra powder 120 mg
- Grifola frondosa powder 80 mg
- Schisandra chinensis powder 80 mg
- Stevia rebaubiana
- Beta vulgaris (root) powder (Beetroot)
- Daucus carota juice dry
- Davidson plum powder
- Backhousia citriodora (leaf) powder
- Kakadu plum powder 80 mg
- Banana resistant starch powder
- Tasmannia lanceolata powder
- Citrus australasica
RRP: $69.95$62.95Save: 10%
Per 10 g:
- Saccharomyces cerevisiae (boulardii) (SB)
- Wheatgrass powder 500 mg
- Brassica oleracea (Broccoli) 400 mg
- Hordeum vulgare powder 500 mg
- Plantago ovata (husk) (Psyllium) 1 g
- Citrus limon (Lemon) 400 mg
- Withania somnifera 750 mg
- Fucus vesiculosus 200 mg
- Zingiber officinale 400 mg
- Actaea racemosa 40 mg
- Rosmarinus officinalis 500 mg
- Ulmus rubra 800 mg
- Silybum marianum 1 g
- Glycyrrhiza glabra 800 mg
- Vitex agnus-castus 500 mg
- Eleutherococcus senticosus 500 mg
- Taraxacum officinale 250 mg
- Stevia rebaubiana 40 mg
- Lactobacillus acidophilus
- Bifidobacterium bifidum
- Lactobacillus casei
- Lactobacillus helveticus
- Lactobacillus bulgaricus
- Lactobacillus leichmannii
- Lactobacillus caucasicus
- Lactococcus lactis
- Lactobacillus fermentum
- Lactobacillus brevis
- Lactobacillus plantarum
- Lactobacillus delbrueckii
- Cinnamon zeylanicum 70 mg
- Punica granatum 250 mg
- Rubus idaeus 300 mg
RRP: $155.80$124.64Save: 20%
Per 15 mL:
- Saccharomyces cerevisiae (boulardii) (SB)
- Syzygium aromaticum
- Zingiber officinale
- Elettaria cardamomum
- Cinnamomum spp.
- Piper nigrum
- Lactobacillus acidophilus
- Lactobacillus casei
- Lactobacillus plantarum
- Lactobacillus bulgaricus
- Lactobacillus fermentum
- Bifidobacterium bifidum
- Bifidobacterium lactis
- Glycerol
- Water
- Punica granatum
- Carica papaya (fruit)
- Carica papaya (leaf)
RRP: $37.46$26.22Save: 30%
Out of stock with supplier
Restock unknown
RRP: $35.95$25.17Save: 30%
RRP: $37.46$26.22Save: 30%
Discontinued by Herbs of Gold
RRP: $89.98$71.98Save: 20%
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This monograph was last reviewed on 22/02/2023 11:00:00 and last updated on 11/11/2020 02:32:16. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
