Background
Some people use parsley for conditions such as bladder infections (UTIs), kidney stones (nephrolithiasis), gastrointestinal (GI) disorders, constipation, skin conditions, and many others. But there is no good scientific evidence to support these uses.
Safety Safety definitions
When applied to the skin: Applying parsley seed oil directly to the skin is LIKELY UNSAFE. It can cause the skin to become extra sensitive to the sun and cause a rash. There isn't enough reliable information to know if applying parsley root and leaf to the skin is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy: It is LIKELY SAFE to consume parsley in food amounts. But parsley in larger medicinal amounts is LIKELY UNSAFE to take during pregnancy. Parsley has been used to cause an abortion and to start menstrual flow. In addition, some research suggests that taking large doses of parsley with other herbs during the first three months of pregnancy can increase the risk of birth defects. If you are pregnant, stick with using only the amount of parsley typically found in food.Breast-feeding: It is LIKELY SAFE to consume parsley in food amounts. There isn't enough reliable information to know if parsley in larger medicinal amounts is safe to use when breast-feeding. Stay on the safe side and stick with the amounts found in foods.
Bleeding disorders: Parsley might slow blood clotting. In theory, taking parsley might increase the risk of bleeding in people with bleeding disorders.
Diabetes: Parsley might lower blood sugar levels. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use parsley.
Fluid retention (edema): There is a concern that parsley might cause the body to hold onto sodium (salt), and this increases water retention.
High blood pressure: There is a concern that parsley might cause the body to hold onto sodium (salt), and this could make high blood pressure worse.
Kidney disease: Don't take parsley if you have kidney disease. Parsley contains chemicals that can make kidney disease worse.
Surgery: Parsley might lower blood glucose levels and could interfere with blood sugar control during and after surgical procedures. Stop using parsley at least 2 weeks before a scheduled surgery.
Effectiveness
Dosing & administration
Interactions with pharmaceuticals
Aspirin
Interaction Rating=Minor Be watchful with this combination.
Some people are allergic to parsley. Aspirin might increase your sensitivity to parsley if you are allergic to parsley. This has only been reported in one person. But to be on the safe side, if you are allergic to parsley do not take aspirin and eat parsley.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Parsley might decrease how quickly the liver breaks down some medications. Taking parsley along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking parsley talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, others), verapamil (Calan, Isoptin, others), and others.
Medications for diabetes (Antidiabetes drugs)
Interaction Rating=Moderate Be cautious with this combination.
Parsley might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking medicinal amounts of parsley along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medications might need to be changed. Some medications for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Moderate Be cautious with this combination.
Parsley might slow blood clotting. Taking parsley along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some anticoagulant/antiplatelet drugs include aspirin, clopidogrel (Plavix), ticagrelor (Brilinta) diclofenac (Voltaren, Cataflam), ibuprofen (Advil, Motrin), naproxen (Anaprox, Naprosyn), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Pentobarbital (Nembutal)
Interaction Rating=Moderate Be cautious with this combination.
Parsley juice might increase the amount of time pentobarbital stays in the body. Taking parsley along with pentobarbital might increase the effects and side effects from pentobarbital.
Sirolimus (Rapamune)
Interaction Rating=Moderate Be cautious with this combination.
Large amounts of parsley juice might increase levels of sirolimus in the body. This could increase the effects and side effects of sirolimus.
Warfarin (Coumadin)
Interaction Rating=Moderate Be cautious with this combination.
Warfarin (Coumadin) is taken to thin the blood and slow blood clotting. Large amounts of parsley leaf might increase blood clotting. Taking parsley along with warfarin might decrease how well warfarin (Coumadin) works to thin the blood.
Water pills (Diuretic drugs)
Interaction Rating=Moderate Be cautious with this combination.
Parsley seems to work like a "water pill" by causing the body to lose water. Taking parsley along with other "water pills" might cause the body to lose too much water. Losing too much water can cause you to be dizzy and your blood pressure to go too low.
Some "water pills" include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), spironolactone (Aldactone), triamterene (Dyrenium), and others.
Interactions with herbs & supplements
Herbs and supplements that might slow blood clotting: Parsley might slow blood clotting. Using it with other herbs or supplements that have this same effect might increase the risk of bruising and bleeding in some people. Some of these products angelica, clove, danshen, fenugreek, feverfew, garlic, ginger, ginkgo, Panax ginseng, poplar, red clover, turmeric, and others.
Interactions with foods
Action
Products
View all products- Petroselinum crispum (Parsley) ext. 10 mg
- Vitex agnus-castus ext. 100 mg
- Melissa officinalis ext. 120 mg
- Perilla frutescens ext. 16.67 mg
- Retinyl palmitate 1.37 mg equiv. vitamin A 750 μgRE
- Riboflavin 5-phosphate sodium (Activated B2) 25 mg equiv. riboflavin 19 mg
- Nicotinamide (Vitamin B3) 50 mg
- Calcium pantothenate (Vitamin B5) 55 mg equiv. pantothenic acid 50.6 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 50 mg equiv. pyridoxine 31.9 mg
- Quercetin 125 mg
- Petroselinum crispum (Parsley) ext. equiv. dry 888 mg
- Crataegus monogyna ext. equiv. dry 711 mg
- Rehmannia glutinosa ext. equiv. dry 711 mg
- Eleutherococcus senticosus ext. equiv. dry 533 mg
- Urtica dioica ext. equiv. dry 888 mg
- Trifolium pratense ext. equiv. dry 711 mg
- Euphrasia officinalis ext. equiv. dry 711 mg
- Taraxacum officinale ext. equiv. dry 711 mg
- Avena sativa ext. equiv. dry 355 mg
- Equisetum arvense ext. equiv. dry 355 mg
- Vaccinium myrtillus ext. equiv. dry 107 mg
- Rosmarinus officinalis ext. equiv. dry 71 mg
- Cinnamomum verum ext. equiv. dry 71 mg
- Syzygium aromaticum ext. equiv. dry 18 mg
- Mentha x piperita oil
- Pimpinella anisum oil
- Glycerol
- Petroselinum crispum (Parsley)
- Rubus idaeus
- Medicago sativa
- Arthrospira platensis (Spirulina)
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Spinacia oleracea
- Fagopyrum esculentum (leaf)
- Chlorella vulgaris powder
- Brassica oleracea var. italica (sprout) powder
- Malus (Apple)
- Ananas comosus (Pineapple)
- Pyrus communis (Pear)
- Citrus limon (Lemon)
- Citrus aurantiifolia (Lime)
- Euterpe oleracea (berry) ext. (Acai)
- Urtica dioica
- Mentha x piperita
- Camellia sinensis
- Apium graveolens
- Cucumis sativus
- Magnesium citrate
- Potassium citrate
- L-glutamine
- Calcium citrate
- Natural flavours
- Taraxacum officinale (leaf) ext. dry
- Eleutherococcus senticosus ext. dry
- Curcuma longa ext. dry
- Withania somnifera ext. dry
- Camellia sinensis ext. dry
- Rosmarinus officinalis ext. dry
- Aloe barbadensis ext. dry
- Gardenia jasminoides ext. dry
- Piper nigrum ext. dry
- Magnesium gluconate
- Apple pectin
- L-alanine
- Xanthan gum
- L-histidine
- Lactobacillus acidophilus
- Bifidobacterium lactis
- Bifidobacterium bifidum
- Bifidobacterium longum
- Potassium ascorbate (Vitamin C)
- Citric acid anhydrous
- Zinc gluconate
- Ferrous fumarate
- Manganese citrate
- Selenomethionine
- Vitamin D
- Chromium picolinate
- Acacia sp. (fibre)
- Petroselinum crispum (Parsley)
- Beef bones
- Sea salt
- Coriandrum sativum
- Origanum vulgare
- Backhousia citriodora (leaf)
- Thymus vulgaris
- Chilli powder
- Curcuma longa
- Piper nigrum
- Mentha x piperita
- Rhus coriaria
- Alpinia galanga
- Cuminum cyminum
- Petroselinum crispum (Parsley) (leaf)
- Oryza sativa (Brown rice sprout, bio-fermented protein)
- Golden pea protein (sprout) bio-fermented
- Garcinia cambogia
- Myristica fragrans (Nutmeg)
- Curcumin (Turmeric)
- Capsicum spp.
- Foeniculum vulgare (seed)
- Arctium lappa (root)
- Stevia rebaubiana (leaf)
- Taraxacum officinale (leaf)
- Eleutherococcus senticosus (root)
- Coleus forskohlii (root)
- Crataegus monogyna (berry)
- Juglans nigra (fruit hull)
- Zingiber officinale
- Fucus vesiculosus
- Stellaria media
- Apple pectin
- Cinnamomum spp.
- Vanilla planifolia (Vanilla bean)
- Laminaria digitara (Kelp)
- Petroselinum crispum (Parsley) powder
- Fermented soybean paste (Miso)
- Daucus carota powder (Carrot)
- Spinacia oleracea (Spinach)
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Pumpkin powder
- Sweet potato powder
- Brassica oleracea var. italica (seed) powder
- Nutritional yeast flakes (Dried yeast)
- Pink Himalayan crystal salt
- Oryza sativa (Brown rice protein)
- Curcuma longa powder
- Arctic sea algae
- Laminaria digitara (Kelp)
- Allium schoenoprasum powder
- Piper nigrum powder
- Sea salt
- Petroselinum crispum (Parsley)
- Fermented soybean paste (Miso)
- Nutritional yeast flakes (Dried yeast)
- Tapioca
- Pink Himalayan crystal salt
- Oryza sativa (Brown rice protein)
- Ganoderma lucidum
- Lentinula edodes
- Curcuma longa powder
- Pumpkin powder
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Spinacia oleracea (Spinach)
- Sweet potato powder
- Daucus carota powder (Carrot)
- Brassica oleracea var. italica (Broccoli)
- Arctic sea algae
- Laminaria digitara (Kelp)
- Allium schoenoprasum
- Piper nigrum
- Aspergillus oryzae (Kōji mould)
- Sodium chloride (Salt)
- Oryza sativa (Brown rice)
- Petroselinum crispum (Parsley)
- Fermented soybean paste (Red miso)
- Oryza sativa (Rice)
- Sea salt
- Aspergillus oryzae (Kōji mould)
- Medium Chain Triglycerides (powder) (MCT)
- Nutritional yeast flakes (Dried yeast)
- Pink Himalayan crystal salt
- Tapioca
- Allium cepa
- Daucus carota powder (Carrot)
- Apium graveolens
- Oryza sativa (Brown rice)
- Allium sativum
- Curcuma longa
- Pumpkin powder
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Spinacia oleracea (Spinach)
- Sweet potato powder
- Brassica oleracea var. italica (Broccoli)
- Laminaria digitara (Kelp)
- Allium schoenoprasum
- Piper nigrum
- Arctic sea algae
- Petroselinum crispum (Parsley)
- Beef bones 9 g
- Apple cider vinegar
- Honey
- Curcuma longa
- Allium sativum
- Chilli powder
- Armoracia rusticana
- Zingiber officinale
- Daucus carota powder (Carrot)
- Apium graveolens
- Allium cepa
- Malus (Apple)
- Orange
- Citrus limon (Lemon)
- Brassica juncea
- Rosmarinus officinalis
- Origanum vulgare
- Thymus vulgaris
- Juniperus communis (berry)
- Piper nigrum
- Pink Himalayan crystal salt
- Sea salt
- Backhousia citriodora
- Bay leaf
- Szechuan pepper
- Petroselinum crispum (Parsley)
- Hordeum vulgare (Barley)
- Green banana starch 250 mg
- Arthrospira platensis (Spirulina)
- Quercetin 200 mg
- Brassica oleracea var. italica (Broccoli)
- Apple pectin 50 mg
- Larix occidentalis (arabinogalactan) (Larch) 250 mg
- Bacillus coagulans 25 mg
- Punica granatum
- Macrocystis pyrifera (Ocean kelp)
- Brassica oleracea var. acephala (leaf & sprout) powder (Kale)
- Spinacia oleracea (Spinach)
- Daucus carota powder (Carrot)
- Brassica oleracea var. viridis
- Palmaria palmata (Dulse)
- Apium graveolens (seed) powder
- Citrus bioflavonoids extract 150 mg
- Myrciaria dubia (fruit) powder (Camu Camu)
- Malpighia glabra
- Blueberry flavour
- Zingiber officinale
- Kakadu plum powder
- Theobroma cacao (Cocoa powder)
- Natural flavours
- Pink Himalayan crystal salt
- Ananas comosus (Bromelain) 150 mg
- Origanum vulgare oil
- Thymus vulgaris oil
- Syzygium aromaticum oil
- Mentha x piperita oil
- N-acetyl glucosamine (NAG) 125 mg
- Stevia rebaubiana
- Zinc citrate 7.5 mg
- Chlorella vulgaris powder
- Polyphenolic fulvic minerals 50 mg
- Petroselinum crispum (Parsley)
- Pea protein concentrate
- Oryza sativa (Rice protein)
- Hordeum vulgare
- Wheatgrass powder
- Amaranth powder
- Quinoa powder
- Medicago sativa
- Malus (Apple)
- Vaccinium corymbosum
- Vaccinium macrocarpon
- Daucus carota powder (Carrot)
- Coriandrum sativum
- Cynara scolymus
- Raphanus raphanistrum (Wild radish)
- Taraxacum officinale
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Apium graveolens
- Beta vulgaris
- Spinacia oleracea (Spinach)
- Lycopersicon esculentum (Tomato)
- Brassica oleracea var. italica
- Armoracia rusticana
- Brassica oleracea var. viridis
- Nasturtium officinale
- Ocimum basilicum
- Piper nigrum
- Mentha spicata
- Natural flavours
- Malpighia glabra ext. dry
- Cordyceps sinensis
- Ganoderma lucidum
- Lentinula edodes
- Grifola frondosa
- Trametes versicolor
- Elettaria cardamomum
- Cinnamomum spp.
- Cannabis sativa (seed) powder
- Agaricus subrufescens
- Stevia rebaubiana
- Petroselinum crispum (Parsley) (root)
- Petroselinum crispum (Parsley) (leaf)
- Juniperus communis (berry)
- Arctostaphylos uva-ursi
- Zea mays
- Taraxacum officinale (root)
- Equisetum arvense
- Eupatorium purpureum
- Solidago virgaurea (flower)
- Hydrangea arborescens (root)
- Mentha x piperita (leaf)
- Althaea officinalis (root)
- Arctium lappa (root)
- Echinacea purpurea (root)
- Orange peel
- Echinacea angustifolia (root)
- Coriandrum sativum
- Petroselinum crispum (Parsley)
- Green banana starch 654 mg
- Wheatgrass powder 654 mg
- Hordeum vulgare (leaf) powder (Barley) 654 mg
- Green lentil
- Mung bean (sprout)
- Spinacia oleracea
- Acacia sp. 1.99 g
- Bacillus subtilis 1 billion CFU
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Cucurbita pepo (seed)
- Linseed
- Chia (seed)
- Cynara scolymus
- Taraxacum officinale (root)
- Chlorella vulgaris 450 mg
- Apple flavour
- Citric acid anhydrous
- Siraitia grosvenorii (Monk fruit)
- Agave sp.
- Arthrospira platensis (Spirulina) 228 mg
- Petroselinum crispum
- Cantharis
- Sepia
- Equisetum hyemale
- Kalium phosphoricum
- Causticum
- Ferrum phosphoricum