Glutathione
Glutathione

Background

Glutathione is a substance made from the amino acids glycine, cysteine, and glutamic acid. It is produced by the liver and involved in many body processes.

Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function.

People take glutathione for aging, alcohol use disorder, liver disease, heart disease, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: Glutathione is possibly safe when used in doses up to 500 mg daily for up to 2 months. There isn't a lot of information available about its possible side effects.

When inhaled: Glutathione is possibly safe. There isn't a lot of information available about its possible side effects.

When applied to the skin: There isn't enough reliable information to know if glutathione is safe. It might cause rash when applied to the skin.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if glutathione is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Asthma: Do not inhale glutathione if you have asthma. It can increase some asthma symptoms.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Nerve damage caused by the drug cisplatin. Taking glutathione by IV seems to help prevent nerve damage and other toxicities from the cancer drug cisplatin. IV products can only be given by a healthcare provider.
There is interest in using glutathione for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of glutathione might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if Glutathione interacts with any medicines. Before taking Glutathione, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
 
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This monograph was last reviewed on 17/10/2023 11:00:00 and last updated on 26/03/2022 08:59:11. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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