Eleuthero
Scientific names: Eleutherococcus senticosus, Acanthopanax senticosus, Hedera senticosa
Family: Araliaceae
Alternative names: Acanthopanax Obovatus, Acanthopanax Obovatus Hoo, Buisson du Diable, Ci Wu Jia, Ciwujia, Ciwujia Root, Ciwujia Root Extract, Devil's Bush, Devil's Shrub, Éleuthéro, Eleuthero Extract, Eleuthero Ginseng, Eleuthero Root, Eleutherococci Radix, Eleutherococcus, Éleuthérocoque, Ginseng, Ginseng de Sibérie, Ginseng des Russes, Ginseng Root, Ginseng Siberiano, Ginseng Sibérien, North Wu Jia Pi, Phytoestrogen, Plante Secrète des Russes, Poivre Sauvage, Prickly Eleutherococcus, Racine d'Eleuthérocoque, Racine de Ginseng, Racine Russe, Russian Root, Shigoka, Siberian Eleuthero, Siberian Ginseng, Eleuthero, Taiga Ginseng, Thorny Bearer of Free Berries, Touch-Me-Not, Untouchable, Ussuri, Ussurian Thorny Pepperbrush, Wild Pepper, Wu Jia Pi, Wu-jia, Wuchaseng
Actions: Adaptogenic mechanism, Antiarthritic, Antibacterial, Antidiabetic, Antifatigue, Antihypoxia, Anti-inflammatory, Antineoplastic, Antioxidant, Antishock, Antistress, Antiulcer, Antiviral, Bone, Cardiovascular, Endocrine, Exercise performance enhancement, Energy metabolism, Gastrointestinal, Hair loss, Hematologic, Hepatoprotective, Immunological, Lipid, Neuroprotective, Nutrition, Radioprotective, Sedative, Toxin protective
Background
Eleuthero (Eleutherococcus senticosus) is a woody shrub sometimes called Siberian ginseng. It is not a true ginseng. It is sometimes used as an adaptogen.
Eleuthero is often considered an adaptogen. Adaptogens are a class of substances that are believed to stimulate the body's resistance to physical, environmental, and emotional stressors. Eleuthero contains many chemicals that affect the brain, immune system, and certain hormones.
People use eleuthero for genital herpes, diabetes, athletic performance, memory and thinking skills, the common cold, and many other conditions, but there is no good scientific evidence to support most of these uses.
Don't confuse eleuthero with other herbs called "ginseng," including American Ginseng, Blue Cohosh, Canaigre, Codonopsis, Panax Ginseng, and Panax Notoginseng. These are not the same.
Eleuthero is often considered an adaptogen. Adaptogens are a class of substances that are believed to stimulate the body's resistance to physical, environmental, and emotional stressors. Eleuthero contains many chemicals that affect the brain, immune system, and certain hormones.
People use eleuthero for genital herpes, diabetes, athletic performance, memory and thinking skills, the common cold, and many other conditions, but there is no good scientific evidence to support most of these uses.
Don't confuse eleuthero with other herbs called "ginseng," including American Ginseng, Blue Cohosh, Canaigre, Codonopsis, Panax Ginseng, and Panax Notoginseng. These are not the same.
Safety Safety definitions
When taken by mouth: Eleuthero is likely safe when used for up to 3 months. Eleuthero is usually well-tolerated. Side effects might include diarrhea, stomach upset, and headache. There isn't enough reliable information to know if eleuthero is safe to use for longer than 3 months.
Children: Eleuthero is possibly safe in teenagers (ages 12-17 years) when taken by mouth for up to 6 weeks. There isn't enough reliable information to know if it is safe to use long-term or in young children.
Heart conditions: Eleuthero might cause a pounding heart, irregular heartbeat, or high blood pressure in people who have heart disorders. If you have a heart condition, only use eleuthero under the supervision of a healthcare provider.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Eleuthero might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use eleuthero.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if eleuthero is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: Eleuthero is possibly safe in teenagers (ages 12-17 years) when taken by mouth for up to 6 weeks. There isn't enough reliable information to know if it is safe to use long-term or in young children.
Heart conditions: Eleuthero might cause a pounding heart, irregular heartbeat, or high blood pressure in people who have heart disorders. If you have a heart condition, only use eleuthero under the supervision of a healthcare provider.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Eleuthero might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use eleuthero.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Genital herpes. Taking a specific eleuthero extract (Elagen) by mouth might help reduce genital herpes outbreaks.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of eleuthero might be. It's often used in combination with other herbs such as Andrographis and Echinacea. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
Digoxin (Lanoxin)
Interaction Rating=Moderate Be cautious with this combination.
There is some concern that eleuthero might increase levels of digoxin. This could increase the effects and side effects of digoxin. If you are taking digoxin, speak with a healthcare provider before taking eleuthero.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Eleuthero might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Eleuthero might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates)
Interaction Rating=Minor Be watchful with this combination.
Some medications are changed and broken down by the liver. Eleuthero might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)
Interaction Rating=Minor Be watchful with this combination.
Some medications are changed and broken down by the liver. Eleuthero might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications for diabetes (Antidiabetes drugs)
Interaction Rating=Moderate Be cautious with this combination.
Eleuthero might lower blood sugar levels. Taking eleuthero along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Medications moved by pumps in cells (Organic anion-transporting polypeptide substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are moved in and out of cells by pumps. Eleuthero might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Medications moved by pumps in cells (P-glycoprotein substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are moved in and out of cells by pumps. Eleuthero might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Medications that decrease the immune system (Immunosuppressants)
Interaction Rating=Moderate Be cautious with this combination.
Eleuthero can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking eleuthero along with these medications might decrease the effects of these medications.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Moderate Be cautious with this combination.
Eleuthero might slow blood clotting. Taking eleuthero along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Interactions with herbs & supplements
Herbs and supplements that might lower blood sugar: Eleuthero might lower blood sugar. Taking it with other supplements with similar effects might lower blood sugar too much. Examples of supplements with this effect include aloe, bitter melon, cassia cinnamon, chromium, and prickly pear cactus.
Herbs and supplements that might slow blood clotting: Eleuthero might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
Herbs and supplements that might slow blood clotting: Eleuthero might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
Interactions with foods
There are no known interactions with foods.
Products
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Per capsule:
- Eleutherococcus senticosus (Siberian ginseng) ext. 116.67 mg equiv. syringaresinol diglucoside 934 μg
- Panax ginseng ext. 18 mg
- Withania somnifera ext. 150 mg
- Panax quinquefolius ext. 12 mg
- Ganoderma lucidum ext. 3.75 mg
- L-phenylalanine 75 mg
- L-tyrosine 75 mg
- Calcium pantothenate (Vitamin B5) 55 mg equiv. pantothenic acid 50 mg equiv. calcium 4.6 mg
- Nicotinamide (Vitamin B3) 15 mg
- Nicotinic acid (Vitamin B3) 5 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 6.74 mg equiv. pyridoxine 4.3 mg
- Calcium folinate (Activated folate) 69.5 μg equiv. folinic acid 50 μg
- Cyanocobalamin (Vitamin B12) 5 μg
Practitioner product
Practitioner product
Practitioner product
Per tablet:
- Eleutherococcus senticosus (Siberian ginseng) ext. 67 mg equiv. syringaresinol diglucoside 533 μg
- Withania somnifera ext. 300 mg
- Nicotinamide (Vitamin B3) 25 mg
- Calcium pantothenate (Vitamin B5) 54.5 mg equiv. pantothenic acid 50 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 19 mg equiv. pyridoxine 12 mg
- d-alpha-Tocopheryl acid succinate 74 mg equiv. vitamin E 90 IU
- Zinc citrate dihydrate 31 mg equiv. zinc 10 mg
- Ascorbic acid (Vitamin C) 75 mg
- Glycyrrhiza glabra ext. 55 mg
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Per tablet:
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Practitioner product
Per scoop (15g) (Tropical):
- Eleutherococcus senticosus (Siberian ginseng) ext. 250 mg
- Medium chain triglycerides (MCT) 1.0 g
- Organic Cracked-Cell Chlorella (1.6% Spermidine) 750 mg
- Organic Alfalfa Grass 600 mg
- Brassica oleracea italica 6 mg
- Silybum marianum ext. 38 mg
- Taurine 1.5 g
- Acetyl L-carnitine (Acetyl-L-carnitine) 500 mg
- L-alpha-glycerylphosphorylcholine (Alpha-GPC) 500 mg
- L-tyrosine 500 mg
- Trimethylglycine (TMG) 500 mg
- Glycine 500 mg
- Nicotinamide riboside chloride (Vitamin B3) 300 mg
- Hyaluronic acid sodium salt (Sodium hyaluronate) 100 mg
- L-theanine 100 mg
- Citrus limon (juice) (Lemon) 737 mg
- Organic Barley Grass 600 mg
- Organic Wheatgrass 500 mg
- Organic Beetroot Juice 36 mg
- Organic Carrot Juice 36 mg
- Organic Kale Leaf (freeze dried) 21 mg
- Organic Spinach Leaf (freeze dried) 21 mg
- Organic Acai Berry (freeze dried) 18 mg
- Organic Apple Juice 6 mg
- Organic Grape Juice 6 mg
- N-acetylcysteine (NAC) 600 mg
- Acacia sp. (gum) 500 mg
- Green banana starch 500 mg
- Bacillus coagulans 15 billion
- Sea Mineral Complex 300 mg
- Thiamine hydrochloride (Vitamin B1) 3 mg
- Riboflavin (Vitamin B2) 2 mg
- Nicotinamide (Vitamin B3) 20 mg
- Calcium pantothenate (Vitamin B5) 5 mg
- Pyridoxine hydrochloride (Vitamin B6) 3 mg
- Biotin 330 µg
- Levomefolate glucosamine (Activated folate) 400 µg
- Methylcobalamin (Activated B12) 220 µg
- Ascorbic acid (Vitamin C) 170 mg
- d-alpha-Tocopheryl acid succinate 80 mg
- Menaquinone 7 (Vitamin K2) 20 µg
- Calcium citrate 307 mg
- Chromium nicotinate 200 µg equiv. chromium 25 µg
- Iron amino acid chelate 18 mg equiv. iron 3.6 mg
- Copper gluconate 2 mg equiv. copper 195 µg
- Magnesium citrate 170 mg equiv. magnesium 34 mg
- Manganese amino acid chelate 4 mg equiv. manganese 400 µg
- Selenomethionine 5 mg equiv. selenium 20 µg
- Zinc citrate 50 mg equiv. zinc 17 mg
- Withania somnifera ext. 300 mg
- Panax ginseng ext. 150 mg
- Camellia sinensis ext. 113 mg
- Theobroma cacao ext. 75 mg
- Vitis vinifera ext. 60 mg
- Rosmarinus officinalis ext. 60 mg
- Centella asiatica ext. 38 mg
- Rhodiola rosea ext. 38 mg
- Organic Lion’s Mane Mushroom 500 mg
- Organic Cordyceps Militaris Mushroom 120 mg
- Organic Reishi Mushroom 120 mg
- Natural pineapple flavour
- Natural flavours
- Stevia rebaubiana
- Xanthan gum
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Per tablet:
- Eleutherococcus senticosus (Siberian ginseng) ext. 133 mg
- Ascorbic acid (Vitamin C) 200 mg
- Pyridoxine hydrochloride (Vitamin B6) 50 mg
- d-alpha-Tocopheryl acid succinate (Vitamin E) 41 mg equiv. d-alpha-tocopherol 34 mg
- Folic acid 500 μg
- Cholecalciferol 10 μg equiv. vitamin D3 400 IU
- Zinc amino acid chelate 25 mg equiv. zinc 5 mg
- Mecobalamin (Vitamin B12) 500 μg
- Calcium pantothenate (Vitamin B5) 75 mg
- Citrus bioflavonoids extract 8.3 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Riboflavin (Vitamin B2) 50 mg
- Nicotinamide (Vitamin B3) 50 mg
- Choline bitartrate 25 mg
- Inositol 25 mg
- Manganese amino acid chelate 10 mg equiv. manganese 1.6 mg
- Borax 8.8 mg equiv. boron 1 mg
- Beta-carotene carotenoids (Vitamin A) 5 mg
- Chromium nicotinate 500 μg equiv. chromium 50 μg
- Potassium iodide 65 μg equiv. iodine 50 μg
- Selenomethionine 65 μg equiv. selenium 26 μg
- Biotin 50 μg
- Silybum marianum ext. 29 mg
- Calcium hydrogen phosphate dihydrate 429 mg equiv. calcium 100 mg
- Magnesium amino acid chelate 150 mg equiv. magnesium 30 mg
- Iron amino acid chelate 25 mg equiv. iron 5 mg
- Potassium phosphate dibasic 4.5 mg equiv. potassium 2 mg
- Copper gluconate 1.2 mg equiv. copper 170 μg
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Per capsule:
RRP: $61.95$49.57Save: 20%
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Per capsule:
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This monograph was last reviewed on 03/10/2024 10:00:00 and last updated on 14/03/2022 07:41:12. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
