Black hoof mushroom
Scientific names: Phellinus linteus
Family: Hymenochaetaceae
Alternate names: Black Hoof Fungus, Mesima, Meshima, Meshimakobu, Sanghuang, Sanghwang, Song Gen
Actions: Antiallergy, Antibacterial, Antidiabetic, Anti-inflammatory, Antilipemic, Antineoplastic, Antioxidant, Cytochrome P450 inhibitory, Gastroprotective, Hepatoprotective, Immune system, Neurologic
Background
Black hoof mushroom (Phellinus linteus) is an orange mushroom that grows on mulberry trees. It has been used as medicine for centuries in Japan, Korea, and China.
Chemicals in black hoof mushroom might block allergic reactions, prevent the growth of bacteria, and protect the liver from toxins. These chemicals might also increase the activity of the immune system in some people.
People use black hoof mushroom by mouth for allergies, arthritis, diabetes, and many other conditions, but there is no good scientific evidence to support these uses. There is also no good evidence to support using black hoof mushroom for COVID-19.
Chemicals in black hoof mushroom might block allergic reactions, prevent the growth of bacteria, and protect the liver from toxins. These chemicals might also increase the activity of the immune system in some people.
People use black hoof mushroom by mouth for allergies, arthritis, diabetes, and many other conditions, but there is no good scientific evidence to support these uses. There is also no good evidence to support using black hoof mushroom for COVID-19.
Safety Safety definitions
When taken by mouth: Black hoof mushroom is possibly safe for most people when taken in doses of 1-2 grams daily for up to 8 weeks.
Autoimmune diseases: Early research suggests that black hoof mushroom might increase immune function. This might make autoimmune disease worse. People with disease such as multiple sclerosis (MS), systemic lupus erythematosus (SLE), or rheumatoid arthritis (RA) should use black hoof mushroom with caution or avoid it altogether.
Enlarged prostate (benign prostatic hyperplasia, BPH): Black hoof mushroom might enlarge the prostate. People who already have this condition should avoid taking black hoof mushroom.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if black hoof mushroom is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Autoimmune diseases: Early research suggests that black hoof mushroom might increase immune function. This might make autoimmune disease worse. People with disease such as multiple sclerosis (MS), systemic lupus erythematosus (SLE), or rheumatoid arthritis (RA) should use black hoof mushroom with caution or avoid it altogether.
Enlarged prostate (benign prostatic hyperplasia, BPH): Black hoof mushroom might enlarge the prostate. People who already have this condition should avoid taking black hoof mushroom.
Effectiveness
Effective Effectiveness definitions
There is interest in using black hoof mushroom for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of black hoof mushroom might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Black hoof mushroom might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates)
Interaction Rating=Moderate Be cautious with this combination.
Some medications are changed and broken down by the liver. Black hoof mushroom might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications that decrease the immune system (Immunosuppressants)
Interaction Rating=Moderate Be cautious with this combination.
Black hoof mushroom can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking black hoof mushroom along with these medications might decrease the effects of these medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 30/03/2023 11:00:00 and last updated on 05/12/2015 03:00:03. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
